China Regenerative Medicine International Limited announced that Ms. Yang and Dr. Fang has tendered their resignations as an independent non-executive Director and a member of each of the audit committee, nomination committee and remuneration committee of the Company all with effect from 30 December 2021 as they desire to devote more time to their other business commitments. The Board announced that the appointment of Mr. Leung and Dr. Liu as an independent non-executive Director of the Company with effect from 30 December 2021. Mr. Leung Man Fai has approximately 30 years of working experience in accounting, corporate finance and corporate management. Mr. Leung graduated from Manchester Polytechnic in the United Kingdom with a degree of Bachelor of Arts in Accounting and Finance awarded by the Council for National Academic Awards of the United Kingdom in July 1988. He also obtained a degree of Master of Commerce in Accounting from the University of New South Wales in May 1990. Mr. Leung was a company secretary of Creative Enterprise Holdings Limited (stock code: 3992) from May 2018 to September 2021, which has been delisted from the Stock Exchange from October 2021. Dr. Liu is currently a special expert of the Hospital in the Department of Otolaryngology. He has more than 25 years of medical clinical and hospital management experience. Dr. Liu has previously served as a general manager of a subsidiary of the Company since May 2018 and resigned from that position in August 2019. The Board further announces that with effect from 30 December 2021: Ms. Yang has ceased to be a member of each of the audit committee, nomination committee and remuneration committee of the Company; Dr. Fang has ceased to be a member of each of the audit committee, nomination committee and remuneration committee of the Company; Mr. Leung has been appointed as a chairman of the audit committee, a member of each of nomination committee and remuneration committee of the Company; and Dr. Liu has been appointed as a chairman of each of nomination committee and remuneration committee and a member of the audit committee of the Company.