Company Denali Therapeutics Inc.

Equities

DNLI

US24823R1059

Biotechnology & Medical Research

Real-time Estimate Cboe BZX 11:41:49 2024-04-26 am EDT 5-day change 1st Jan Change
15.25 USD +1.94% Intraday chart for Denali Therapeutics Inc. -4.16% -28.54%

Business Summary

Denali Therapeutics Inc. is a biopharmaceutical company. The Company is focused on developing a portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for neurodegenerative diseases and lysosomal storage disease. The Company has a portfolio of both small molecule and biotherapeutic medicines, comprising seven product candidates in clinical development across seven indications as well as preclinical therapeutic candidates. Its three late-stage development programs include tividenofusp alfa (DNL310) for mucopolysaccharidosis II (MPS II); BIIB122/DNL151 (LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (eIF2B activator) for amyotrophic lateral sclerosis (ALS). SAR443820/DNL788 (RIPK1 inhibitor) is being evaluated in a Phase II study for multiple sclerosis (MS). In addition, it has a Phase I/II study of TAK-594/DNL593 for frontotemporal dementia-granulin (FTD-GRN) and a Phase I/II study of DNL126 for MPS IIIA (Sanfilippo syndrome).

Number of employees: 445

Sales per Business

USD in Million2022Weight2023Weight Delta
Therapeutics
100.0 %
108 100.0 % 331 100.0 % +204.74%

Sales per region

USD in Million2022Weight2023Weight Delta
United States
100.0 %
108 100.0 % 331 100.0 % +204.74%

Managers

Managers TitleAgeSince
Founder 50 13-10-13
Founder 48 13-10-13
Chief Tech/Sci/R&D Officer - 19-12-31
Chief Tech/Sci/R&D Officer - 18-08-06
Chief Tech/Sci/R&D Officer 51 15-05-31
Director/Board Member 56 15-09-30
Investor Relations Contact - -
Corporate Officer/Principal - 21-09-26
General Counsel - -
General Counsel - -

Members of the board

Members of the board TitleAgeSince
Chairman 75 15-03-31
Director/Board Member 71 15-03-31
Director/Board Member 66 15-03-31
Founder 64 13-10-13
Director/Board Member 58 18-11-05
Director/Board Member 61 18-03-15
Director/Board Member 54 22-02-06
Director/Board Member 56 15-09-30
Director/Board Member 67 21-01-07
Founder 48 13-10-13

Share class

VoteQuantityFree-FloatCompany-owned sharesTotal Float
Stock A 1 142,539,529 122,839,616 ( 86.18 %) 0 86.18 %

Shareholders

NameEquities%Valuation
Baillie Gifford & Co.
10.25 %
14,260,724 10.25 % 293 M $
12,751,365 9.163 % 262 M $
Vanguard Fiduciary Trust Co.
7.786 %
10,834,483 7.786 % 222 M $
BlackRock Advisors LLC
7.607 %
10,585,444 7.607 % 217 M $
Wellington Management Co. LLP
5.228 %
7,274,717 5.228 % 149 M $
Temasek Holdings Pte Ltd.
4.955 %
6,895,992 4.955 % 142 M $
Crestline Management LP
4.068 %
5,660,732 4.068 % 116 M $
5,485,948 3.942 % 113 M $
4,214,559 3.029 % 86 M $
Capital Research & Management Co. (Global Investors)
2.091 %
2,909,528 2.091 % 60 M $

Company contact information

Denali Therapeutics, Inc.

161 Oyster Point Boulevard

94080, San Francisco

+650 866 8548

http://www.denalitherapeutics.com
address Denali Therapeutics Inc.(DNLI)
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