eFFECTOR Therapeutics, Inc. announced it has appointed Douglas Warner, M.D., as chief medical officer. Dr. Warner will develop strategies to continue advancing eFFECTOR's two clinical-stage STRIs into advanced and potentially registrational trials. Dr. Warner will be responsible for overseeing eFFECTOR's ongoing clinical trials, including its KICKSTART Phase 2b trial of tomivosertib in combination with pembrolizumab in non-small cell lung cancer, its Phase 1/2 study of zotatifin in oncology and its Phase 1 study of zotatifin in COVID-19.

He will also be responsible for developing registration strategies for both programs and exploring expansion into additional oncology indications. Prior to eFFECTOR, Dr. Warner held roles of increasing responsibility over 18 years at Amgen where he oversaw extensive clinical development programs in multiple indications across oncology and general medicine. In his most recent position, Executive Medical Director, Group Product Area Lead, Dr. Warner provided development guidance and oversight over a broad portfolio of solid tumor immune-oncology and pathway inhibitor development programs that ranged from phase 1 to marketed products.

Prior to this position, Dr. Warner was the Global Development Lead for several products including Vectibix®, XGEVA®, and Prolia®.   In this role, Dr. Warner led evidence generation and oversaw the design, execution, and analysis of studies across the phases of development, including large global phase 3 trials, and was the clinical development leader for major regulatory filings worldwide. Dr. Warner is co-author on numerous peer-reviewed articles including those in The Lancet, The Lancet Oncology, and The Journal of Clinical Oncology. He received his B.A. from the University of Pennsylvania, his M.D. from the Duke University School of Medicine, and his M.B.A. from the UCLA Anderson School of Management.