On December 27, 2023, Mr. Tomer Kariv notified the Board of Directors (the Board") of Eloxx Pharmaceuticals, Inc. of his resignation from the Board and his position as Chairman of the Board and from the committee of the Board on which he serves. The resignation is effective as of December 27, 2023 and did not result from any disagreement with the Company on any matter relating to the Company's operations, policies or practices.