MADISON, Wis. (AP) — MADISON, Wis. (AP) — Exact Sciences Corp. (EXAS) on Wednesday reported a loss of $49.8 million in its fourth quarter.

On a per-share basis, the Madison, Wisconsin-based company said it had a loss of 27 cents.

The results beat Wall Street expectations. The average estimate of six analysts surveyed by Zacks Investment Research was for a loss of 53 cents per share.

The molecular diagnostics company posted revenue of $646.9 million in the period, also topping Street forecasts. Seven analysts surveyed by Zacks expected $631.9 million.

For the year, the company reported a loss of $204.1 million, or $1.13 per share. Revenue was reported as $2.5 billion.

Exact Sciences expects full-year revenue in the range of $2.81 billion to $2.85 billion.

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