Oslo, 5 December 2021

Masha Strømme, chair of EXACT Therapeutics AS has on 2 December 2021 acquired 2
498  shares at an average price of NOK 16.0196 and on 3 December 2021 acquired 1
772 shares at an average price of NOK 17.1806, in EXACT Therapeutics AS. The
shares were acquired through PAACS Invest AS,  Dr. Strømme's investment company.
Following the transaction, Dr. Strømme controls 2 689 009 shares in EXACT
Therapeutics AS.

EXACT THERAPEUTICS AS - MANDATORY NOTIFICATION OF TRADE BY PRIMARY INSIDER
Oslo, 5 December 2021

Svein Kvåle, COO and Co-Founder of EXACT Therapeutics AS has on 2 December 2021
acquired 2 498  shares at an average price of NOK 16.0196 and on 3 December 2021
acquired 1 772 shares at an average price of NOK 17.1806, in EXACT Therapeutics
AS. The shares were acquired through Kvåle AS, a company controlled by Dr.
Kvåle. Following the transaction, Dr. Kvåle controls  3 021 770 shares in EXACT
Therapeutics AS.

EXACT THERAPEUTICS AS - MANDATORY NOTIFICATION OF TRADE BY PRIMARY INSIDER
Oslo, 5 December 2021

Andrew J. Healy, CSO and Co-Founder of EXACT Therapeutics AS has on 2 December
2021 acquired 1 249 shares at an average price of NOK 16.0196 and on 3 December
2021 acquired 886 shares at an average price of NOK 17.1806, in EXACT
Therapeutics AS. Following the transaction, Dr. Healy controls 2 205 385 shares
in EXACT Therapeutics AS.

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