On April 21, 2023, Gary A. Lyons informed Fresh Tracks Therapeutics, Inc. that he will resign from the Board of Directors on the date of the Company's 2023 annual meeting of stockholders, because of overboarding concerns under proxy advisor and other institutional investor policies. The date of the Company's 2023 annual meeting of stockholders has not yet been determined. Mr. Lyons' decision to resign is not the result of any disagreement on any matter relating to the operations, policies or practices of the Company.