Item 1.01 Entry into a Material Definitive Agreement.

On April 16, 2021, Galectin Therapeutics Inc. (the "Company") and Richard E. Uihlein entered into a debt financing arrangement whereby Mr. Uihlein loaned ten million dollars to Company. In consideration for the loan, the Company issued a convertible promissory note (the "Note") in the principal amount of ten million dollars.

The Note has maturity date of April 16, 2025 and is convertible into the Company's common stock at a conversion price equal to $5.00 per share at the option of the noteholder. The Note bears interest on at the rate of two percent (2%) per annum, compounded annually, and accrues additional interest at a rate of two and one-half percent (2.5%) per quarter (the "Additional Interest") beginning on the date of issuance of this Note and ending on the maturity date, provided however, that such Additional Interest is payable if and only if the noteholder elects to convert the entire balance of the Note into the Company's common stock.

The foregoing description of the Note does not purport to be complete and the terms of the Note is subject to, and qualified in its entirety by reference to the Convertible Note which is filed herewith as Exhibit 10.1, and is incorporated herein by reference.

Item 2.03. Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of Registrant.

The information contained in Item 1.01 above is incorporated herein by reference.

Item 3.02 Unregistered Sales of Equity Securities.

The information contained in Item 1.01 above is incorporated herein by reference.

The sale and issuance of the Note as disclosed in Item 1.01 of this Current Report on Form 8-K has been determined to be exempt from registration under the Act in reliance on Section 4(2) of the Act and Rule 506 of Regulation D promulgated under the Act.

Item 7.01 Regulation FD Disclosure

On April 16, 2021, the Company entered into a consulting agreement with renowned neurosurgeon, Ben Carson, Sr. M.D. Dr. Carson was most recently the United States Secretary of Housing and Urban Development from March 2017 to January 2021. Dr. Carson was engaged by the Company to provide continuing consulting services to the Company regarding the development program of belapectin with special emphasis on (a) increasing awareness of the Company, its clinical trials, and the medical needs that such trials are addressing, (b) in assisting in the formation of a scientific advisory committee for the Company and identification of potential members of such committee, (c) assisting the Company in finding strategic commercial and/or academic partners to further its research and clinical trials in oncology and other fields, and (d) periodically acting as a spokesperson related to the Company's science through public comments and interviews, in introductions to commercial and academic partners, and in other public statements as may be requested.





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Item 9.01 Financial Statements and Exhibits.





Exhibit No.

10.1                Convertible Promissory Note, dated April 16, 2021

104               Cover Page Interactive Data File (embedded within the Inline XBRL
                  document).




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