Item 1.01 Entry into a Material Definitive Agreement.

On September 27, 2021, HTG Molecular Diagnostics, Inc. (the "Company") entered into a Third Amendment to its Standard Commercial-Industrial Multi Tenant Triple Net Lease, dated July 11, 2008, with Pegasus Properties L.P. (the "Suite 300 Lease"), related to the Company's corporate facilities located at 3430 E. Global Loop, Suite 300, Tucson, Arizona 86706 (the "Third Amendment").

On September 27, 2021, the Company also entered into a Fourth Amendment to its Standard Commercial-Industrial Multi Tenant Triple Net Lease, dated May 11, 2011, with Pegasus Properties L.P. (the "Suite 100 Lease"), related to the Company's corporate facilities located at 3400 E. Global Loop, Suite 100, Tucson, Arizona 86706 (the "Fourth Amendment").

Pursuant to the Third Amendment, the term of the Suite 300 Lease was extended for a period of three years to January 31, 2025. The monthly base rent under the Suite 300 Lease for the period from February 1, 2022 through January 31, 2025 will be $15,735 per month. The Company will have an option to renew the Suite 300 Lease for an additional two year period on the same terms and conditions as the existing Suite 300 Lease, as amended by the Third Amendment, except that lease rates would be adjusted to rates applicable to like-kind buildings within the market at the time the Company elects to exercise the extension option, but in no event to less than the last applicable rental rate.

Pursuant to the Fourth Amendment, the term of the Suite 100 Lease was extended for a period of three years to January 31, 2025. The monthly base rent under the Suite 100 Lease for the period from February 1, 2022 through January 31, 2025 will be $24,500 per month. The Company will have an option to renew the Suite 100 Lease for an additional two year period on the same terms and conditions as the existing Suite 100 Lease, as amended by the Fourth Amendment, except that lease rates would be adjusted to rates applicable to like-kind buildings within the market at the time the Company elects to exercise the extension option, but in no event to less than the last applicable rental rate.

The foregoing summaries of the Third Amendment and Fourth Amendment do not purport to be complete descriptions of these documents, and are qualified in their entirety by the Third Amendment and Fourth Amendment, copies of which are filed as Exhibits 10.1 and 10.2 to this report.

Item 9.01Financial Statements and Exhibits.

(d) Exhibits



Exhibit
Number    Description
10.1        Third Amendment, dated September 27, 2021, to Standard
          Commercial-Industrial Multi Tenant Triple Net Lease, dated
          July 11, 2008, between the Company and Pegasus Properties
          L.P  .

10.2        Fourth Amendment, dated September 27, 2021, to Standard
          Commercial-Industrial Multi Tenant Triple Net Lease, dated May
          11, 2011, between the Company and Pegasus Properties L.P  .

104       The cover page of this report has been formatted in Inline XBR



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