Impel NeuroPharma, Inc. announced the appointments of Leonard S. Paolillo as chief commercial officer and Gerald F. Penn as vice president, market access and trade. These key management additions further the build out of the commercial infrastructure of the organization as it prepares for the potential launch of TRUDHESA for the acute treatment of migraine headaches with or without aura in adults later this year, subject to U.S. Food and Drug Administration (FDA) approval. Mr. Paolillo joins Impel NeuroPharma from Kyowa Kirin Inc., the North American affiliate of Kyowa Kirin Co. Ltd., a global specialty pharmaceutical company based in Tokyo, Japan where he served as executive vice president, chief commercial officer. He was responsible for the growth and transformation of the commercial infrastructure to enable the successful launches of the company's pipeline products in hematology/oncology, CNS, and rare disease, which led to more than a 15-fold increase in revenue from 2017 - 2020. Prior, he served as senior director of sales at Warner Chilcott Pharmaceuticals where he led the women's healthcare, osteoporosis and urology sales forces with 29 districts and 300+ representatives. Mr. Paolillo began his healthcare career at EURO RSCG LIFE LM&P, a full-service healthcare advertising agency and holds a B.S. in business administration from Manhattan College. Mr. Penn joins Impel NeuroPharma from Esperion Therapeutics, Inc. where he served as vice president of market access and trade and was integral in building out a new commercial department, including managing a team of senior account, contracting and government directors to secure reimbursement and distribution for a new small oral molecule and combination product in the LDL Lipid Market. Prior he served as executive director, market access at Aralez Pharmaceuticals, Inc. where he helped launch the company in the U.S. market and assisted with distribution, trade, pricing, product package design and market access strategy for commercial, Part D, and Medicaid plans. Prior to Aralez, Mr. Penn held sales and market access positions at Kaleo, Auxilium Pharmaceuticals, American Regent, Kos Pharmaceuticals, Forest Laboratories, ICI Pharma, Smith Corona Corporation and Schmid Laboratories. Mr. Penn holds a B.S. in marketing from Northern Illinois University.