On June 1, 2022, Gail Cawkwell, M.D., Ph.D., notified Intercept Pharmaceuticals, Inc. of her decision to resign from her position as the Company's Senior Vice President, Medical Affairs, Safety & Pharmacovigilance, in order to pursue other opportunities. Dr. Cawkwell's resignation was not the result of any disagreement regarding any matter related to the Company's operations, policies or practices.