Invion Limited announced that an International Patent Application, which includes the lead compound INV043, has been published. This patent builds upon previously granted PhotosoftTM related patents in Australia and other territories that Invion has exclusive rights to. The new patent, upon approval, will extend the global intellectual property (IP) protection for the PhotosoftTM technology for another two decades (the original patents are set to expire in 2033).

Pre-clinical proof of concept studies of INV043, which is covered by this patent, conducted by Hudson Institute of Medical Research found: INV043 to be effective at ablating multiple types of cancer including triple negative breast cancer (TNBC), pancreatic and T-cell lymphoma Complete regression of established TNBC tumours in mice and provide protective immunity against recurrence of disease following treatment with INV043 Significant improvement in the effectiveness of immune checkpoint inhibitors (ICI), an established type of immunotherapy used in cancer treatment, when used in combination with a restricted administration of INV043. The patent application comes at an important juncture for Invion as the Company is preparing to undertake clinical trials using INV043 to treat cancers and opens up opportunities to combine INV043 with other established cancer therapies to improve patient outcomes. The new patent broadens commercial opportunities for Invion that include both: · Development of INV043 as a standalone therapy, and · Opens partnership opportunities with international pharmaceutical companies to develop combination therapies, such as INV043 and ICI's, potentially broadening the patient population who can benefit from such treatments.

The newly filed patent covering clinical drug candidate INV043 has now progressed to the international examination phase. The application was filed by licensor and funder, RMW Cho Group Limited, pursuant to the Patent Cooperation Treaty (PCT), as the next phase in obtaining new patents in markets globally, including Australia and other territories that Invion has exclusive commercialising rights to. The findings of the International Search Report and associated Written Opinion from the European Patent Office considered the claims relating to INV043 as novel, inventive and meet the requirements for industrial applicability.