Invion Limited announce the positive screening results from in vitro studies of PhotosoftTM on the inhibition of the Dengue virus. The tests, which were done on ten PhotosoftTM photodynamic compounds at eight concentrations, found that eight of the 10 compounds displayed antiviral activity against the Dengue virus after exposure to a specific light wavelength (660nm). The EC50 (half maximal effective concentration) values of the eight PhotosoftTM compounds that showed antiviral activity ranged between 11.1nM and 539nM. These values were significantly below that of Monensin (1031nM), an antibiotic with known activity against Dengue virus was used as a control. None of the compounds were antiviral in the absence of
this light source.