On June 8, 2021, Dr. Shahzad Malik, a director of Iterum Therapeutics plc, notified the company of his resignation from the board of directors of the company, effective immediately. Dr. Malik also served as a member of the company’s compensation and nominating and governance committees. Dr. Malik’s resignation was not the result of any dispute or disagreement with the company or the company’s board on any matter relating to the operations, policies or practices of the company. Following Dr. Malik’s resignation, the board approved a decrease in the size of the Board from eight to seven directors and as a result, there is not currently a vacancy on the Board.