Kymera Therapeutics, Inc. announced that its preclinical data demonstrating the therapeutic potential of its potent and selective heterobifunctional degraders of STAT6 (KT-621) and TYK2 (KT-294) are being presented in the poster session at the American Academy of Dermatology's Annual Meeting in San Diego, California. Kymera's oral STAT6 and TYK2 degraders have the potential to address multiple immune-mediated diseases and overcome the limitations of existing technologies and agents. The company plans to share additional preclinical data for KT-621 and KT-294 at upcoming medical meetings in 2024.

Copies of both poster presentations entitled " Potent and Selective Oral STAT6 Degraders Inhibit IL-4 and IL-13 Functions in Human Cells and Block TH2 Inflammation in a Mouse Model of Atopic Dermatitis " and " Potent and Selective TYK2 Degraders, Devoid of JAK Activity, Potently and Completely Suppress IL-12/23 and Type I IFN Signaling Pathways" are available in the Resource Library section of Kymera's website.