Ladenburg -
Prof.
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By building a platform that will target critical areas of uncovered medical
About
Antibody-drug conjugates (Antibody Drug Conjugates - ADCs) combine the high Affinity and specificity of antibodies with the effectiveness of small toxic molecules, to fight cancer. ATACs (Antibody Targeted Amanitin Conjugates) are ADCs whose Active ingredient consists of amatoxin molecules. Amatoxins are bicyclic peptides found in the Naturally occurring in the green leaf agaric. By binding to the RNA polymerase II
They inhibit the transcription of the mRNA, a mechanism that is crucial for the Survival of eukaryotic cells is. In preclinical studies, ATACs have a very shown to be highly effective; they overcame common mechanisms of resistance and can also fight dormant tumor cells.
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Email: investors [at] hdpharma.com
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