OBI Pharma, Inc. announced director changes. Name of the previous position holder: Director Michael Chang, Representative of Yi Tai Investment Co. Ltd. Director Tamon Tseng, Representative of Yi Tai Investment Co.

Ltd. Director Yun Yen, Representative of Sheng Cheng Investment Co. Ltd. Director Frank Chen, Representative of Sheng Cheng Investment Co. Ltd. Independent Director Jerry Fong, Independent Director Taychang Wang, Independent Director Howard Lee.

name of the new position holder: Director Michael Chang Director Tamon Tseng, Representative of Yi Tai Investment Co. Ltd. Director Yun Yen, Representative of Sheng Cheng Investment Co. Ltd. Director Frank Chen, Representative of Sheng Cheng Investment Co.

Ltd. Independent Director Howard Lee Independent Director Ming-Chin Chen Independent Director Chin-Ting Chiu. Resume of the new position holder: Director Michael Chang /Chairman of the Board and CEO, OBI Pharma Inc. Director Tamon Tseng, Representative of Yi Tai Investment Co., Ltd/Special Assistant to Legal Division, Ruentex Group Director Yun Yen, Representative of Sheng Cheng Investment Co. Ltd./Chairman of the Board, Tanvex BioPharma, Inc. Director Frank Chen, Representative of Sheng Cheng Investment Co.

Ltd./Vice President, Investment Management Department and Special Assistant to President, Ruentex Group Independent Director Howard Lee /Chairman of the Board, TAHO Pharmaceuticals Ltd. Independent Director Ming-Chin Chen /Accounting Professor, National Chengchi University Independent Director Chin-Ting Chiu /Member of Mediation Committee, Securities and Futures Investors Protection Center. Date of occurrence of the change: June 27, 2022.