OpSens Inc. announce the successful treatment of 20 patients leading to the completion of the first in-man clinical study utilizing the SavvyWire. The wire was designed and developed to improve the intervention workflow for transcatheter aortic valve replacement ("TAVR") and is the first guidewire able to both deliver a valvular prosthesis while allowing continuous hemodynamic pressure measurement during the procedure. The SavvyWire is not yet approved for commercialization. Aortic valve stenosis occurs when the heart's aortic valve narrows, which prevents the valve from opening fully, restricting blood flow from the heart into the main artery (aorta) and onward to the rest of the body. Initially, the TAVR procedure was only indicated for inoperable patients and then for high-risk surgical patients. Clinical programs like ''PARTNER III'' and ''Evolut Low Risk'', have since shown better or equivalent clinical outcomes in intermediate and low-risk patients. The TAVR procedure is now evolving quickly with a minimalist approach that allows the procedure to be faster and the patients to be discharged earlier, sometimes on the same day.