Plandaí Biotechnology, Inc. Addresses Bioavailability and the Science of Phytofare from Previous Human Clinical Trial Results
April 10, 2018 at 08:30 am EDT
Share
Plandaí Biotechnology, Inc. provided an update and recap of its bioavailability and the science and key benefits of Phytofare from previous human clinical trial results. According to the trial results, Phytofare® delivered an average catechin concentration of 14,786 ng/ml compared to a concentration of 930 ng/ml delivered by the standard green tea extract. This is almost a 15-fold greater average concentration than was delivered by the generic comparator. The total concentration of Epigallocatechin Gallate (EGCG) delivered by Phytofare was 153,011 ng/ml compared to a total concentration of 15,921 ng/ml EGCG delivered by the standard green tea extract, a 10-fold greater total concentration. EGCG is regarded as a key catechin and has been linked to a variety of possible wellness effects, including weight loss, anti-viral activity, cancer prevention, and blood sugar regulation in diabetics. With respect to blood plasma residency, Phytofare® was still active in the system 24 hours after consumption. In the case of EGCG, after 24 hours the Phytofare® levels were 256ng/ml compared to 16ng/ml for the generic, a 16-fold increase. In fact, after 24 hours there was still nearly 1.5 times as much Phytofare® EGCG in the blood as was present from the generic extract at its highest recorded level (265ng/ml compared to 181ng/ml). This means that a therapeutic level of Phytofare® can be achieved from a once-per-day dose whilst standard green tea would require multiple doses of far greater size throughout the day to deliver the same levels of catechins. Where catechins consumed at high levels (greater than 800mg) can cause nausea and other side effects, being able to deliver therapeutic levels with a smaller dose is a huge benefit to the consumer. Thirdly, the clinical trial showed that all eight primary catechins were present in the blood from the Phytofare®, while only three catechins were detected with the generic. This means that consumers get the synergistic effects of the entire phytonutrient profile with Phytofare® whereas these benefits are lost with generic extract through processing and metabolization.
Plandai Biotechnology, Inc. is a biotech company, which is focused on the production of botanical extracts for the nutraceutical and pharmaceutical industries. The Company grows the green tea used in its products on a 3,000-hectare estate in the Mpumalanga region of South Africa. Its marketed product, Phytofare Catechin Complex, is a green-tea-derived extract that has multiple potential wellness applications. It caters to airline flights and operated coffee shops, lounges and gift shops at airports, and other facilities located in Florida, Alabama, and Georgia. Its airline catering services include the preparation of meals in kitchens located at, or adjacent to, airports and the distribution of meals and beverages for service on commercial airline flights. The Company also provides certain ancillary services, including the preparation of beverage service carts, the unloading and cleaning of plates, utensils and other accessories arriving on incoming aircraft, and other.
PLANDAÍ BIOTECHNOLOGY, INC. 
