RespireRx Pharmaceuticals Inc. announced that, as part of an ongoing collaboration, a scientist team led by Dr. David Fuller of the University of Florida has published a peer-reviewed research article describing the ability of CX1739, the Company's lead clinical-stage AMPAkine (AMPA glutamate receptor potentiator), to restore bladder function in rodents that have undergone spinal cord injury (SCI). Traumatic SCI often results in neurogenic bladder dysfunction that causes urological complications such as urinary infection, kidney damage and bladder cancer, reduces the quality of life and places patients with these injuries at increased risk of premature death. In a series of important studies funded by grants from the National Institutes of Health and published in a number of peer reviewed articles, he has demonstrated the ability of RespireRx's lead AMPAkines to improve motor nerve activity and muscle function in a number of animal models of spinal cord injury (SCI), including first respiration and now bladder functions.

Depending on additional funding which are seeking to raise, but cannot assure the company will achieve, the company have begun planning to conduct a translational, Phase 2 clinical study in SCI patients late this year. The company believe that this research has the potential to represent a novel, breakthrough in the treatment of SCI patients late thisyear. The company believes that this research has the potential To represent a novel, novel, low impact AMPAkines, including CX717, CX1739 and CX1942 that may have clinical application in the treatment of CNS-driven neurobehavioral and cognitive disorders, spinal cord injury, neurological diseases, and certain orphan indications.

AMPAkines have demonstrated positive activity in animal models of ADHD, results that have been extended translationally into statistically significant improvement of symptoms observed in a Phase 2 human clinical trial of CX717 in adult patients with ADHD. ResolutionRx will now engage in the research and development associated with that program, initially for the development of a new formulation of dronabinol for use in a Phase 3 clinical trial and the filing of regulatory approval for the treatment of obstructive sleep apnea ("OSA"). Dronabinol, an endocannabinoid receptor agonist, has already demonstrated significant improvement in the symptoms of OSA in two Phase 2 clinical trials.

Because dronabinol is already FDA approved for the treatment of AIDS related anorexia and chemotherapy induced nausea and vomiting, RespireRx and ResolutionRx further believe that its repurposing strategy would only require, in the United States, approval by the FDA of a 505(b)(2) new drug application ("NDA"), an efficient regulatory pathway that allows the use of publicly available data. These might include statements regarding the Company's future plans, targets, estimates, assumptions, financial position, business strategy and other plans and objectives for future operations, and assumptions and predictions about research and development efforts, including, but not limited to, preclinical and clinical research design, execution, timing, costs and results, future product demand, supply, manufacturing, costs, marketing and pricing factors. In some cases, forward-looking statements may be identified by words including "assumes," "could," " ongoing, ongoing, ongoing, potential, " potential," "predicts," "projects," "should," "will," "will," "will"), "would," "ant anticipates," "ant anticipates," 'intends," "estimates," "estimates," "the company's broad patent portfolios for two drug platforms.