On 1 December 2022, Hainan SinoMab entered into a supplemental lease agreement with Haikou Pharma, pursuant to which the annual rental of the Property and the Equipment will be increased from RMB 4,959,305 to RMB 9,400,000 with effect from 1 January 2022. the Lease Agreement entered between SinoMab BioScience (Hainan) Limited and Haikou Pharma. Unless otherwise stated, capitalised terms used herein shall have the same meaning as defined in the Prospectus.

Pursuant to the Lease Agreement, Haikou Pharma agreed to lease the Property and the Equipment (as defined below) to the Group from 1 January 2019 to 31 December 2025.