SkinBioTherapeutics plc announced that interim data from the AxisBiotix Acne food supplement consumer participant study with the lead formulation are very positive. The Company will continue the study to completion. The analysis and read-out of the final results is anticipated to occur before the end of First Quarter 2024.

The volunteer study, comprising 220 people, followed the same methodology to the AxisBiotix-Ps study, with the supplement containing the lead formulation, being supplied to participants in powder-form. Participants were then asked to record scores against specific criteria on an app. The scoring criteria included severity of acne, level of pain, attitude to appearance and levels of confidence.

The full study length is 56 days to reflect the time it takes for the skin to replenish itself completely. In people, the number of days ranges from 40-56 days, depending on age and location, therefore the maximum time was chosen for the study. While results at this interim point are positive, there can be no certainty that these will either improve or be maintained.

The completion of the full study and analysis of the total data set is required to understand the outcomes. The study is being conducted by an independent third-party, and the supplement blend has been formulated and manufactured by the Dutch food supplement provider Winclove Probiotics BV. Although not life-threatening, acne can cause irritation and life-long scarring, and can negatively impact a person's mental health and self-esteem.

Acne develops when pores get clogged with dead skin, bacteria, and dried skin oil buildup, which leads to redness, tenderness, pimples, nodules, or cysts primarily on the face, back, or chest. Acne can range from mild to severe and typically affects teenagers and young adults but anyone can be affected. Treatment of severe acne often requires topical steroid creams which can lead to undesirable side effects, including skin dryness, irritation, and rashes.

Alternative treatments include oral medications where side effects can be more severe e.g. depression or suicidal thoughts.