Inactive Instrument

Stealth BioTherapeutics Corp

Equities

MITO

US85789A1051

Biotechnology & Medical Research

Stealth BioTherapeutics Corp Announces SBT-272 Data Updates and Orphan Drug Designation for the Treatment of Amyotrophic Lateral Sclerosis

November 01, 2022 at 07:30 am EDT

Stealth BioTherapeutics Corp. announced encouraging Phase 1 data on the safety and tolerability of SBT-272, a next- generation small molecule designed to reach therapeutic concentrations in the brain and to restore mitochondrial structure and function. The Company also announced that positive preclinical data demonstrating that treatment with SBT-272 provided neuroprotection of upper motor neurons harboring ALS pathology will be presented at the Northeast Amyotrophic Lateral Sclerosis conference in Clearwater, FL.

The Company recently received Orphan Drug Designation from the US Food and Drug Administration Office of Orphan Products Development for SBT-272 for the treatment of patients with ALS.

Latest news about Stealth BioTherapeutics Corp

Stealth BioTherapeutics Corp Highlights Opportunities and Challenges in Ultra-Rare Disease Drug Development at World Orphan Drug Congress USA	23-06-14	CI
Stealth BioTherapeutics Announces Positive End-Of-Phase 2 Meeting with FDA on the Development of Elamipretide in Patients with Dry Age-related Macular Degeneration	23-06-12	CI
Stealth Biotherapeutics Enters into Exclusive Licensing Agreement with Pharmanovia to Commercialize Elamipretide	23-05-30	CI
Stealth BioTherapeutics Corp(NasdaqGM:MITO) dropped from NASDAQ Composite Index	22-11-16	CI
J. Wood Capital Advisors LLC and Morningside Venture (I) Investments Limited completed the acquisition of 22.5293% stake in Stealth BioTherapeutics Corp.	22-11-15	CI
Stealth BioTherapeutics Corp Announces SBT-272 Data Updates and Orphan Drug Designation for the Treatment of Amyotrophic Lateral Sclerosis	22-11-01	CI
Stealth BioTherapeutics Chief Financial Officer Departs	22-10-03	MT
Stealth BioTherapeutics Corp Announces Departure of Robert Weiskopf as Chief Financial Officer	22-09-30	CI
Stealth BioTherapeutics Corp Agrees to Go Private; Shares Jump	22-08-01	MT
Stealth BioTherapeutics Gets Notice of Potential Delistment From Nasdaq	22-07-12	MT
Stealth BioTherapeutics Receives Non-Binding Proposal by Morningside Venture to Go Private	22-06-27	MT
J. Wood Capital Advisors LLC and Morningside Venture (I) Investments Limited agreed to acquire a 22.5293% stake in Stealth BioTherapeutics Corp for $0.35 million.	22-06-26	CI
Sector Update: Health Care Stocks Climb Pre-Bell Tuesday	22-06-14	MT
Sector Update: Health Care	22-06-14	MT
Stealth BioTherapeutics Gets FDA Meeting on Pre-Application for Potential Barth Syndrome Treatment	22-06-14	MT
Stealth BioTherapeutics Granted Pre-NDA Meeting for Elamipretide as a Potential Treatment for Barth Syndrome	22-06-14	CI
Wall Street Tumbles Pre-Bell; Inflation Data Eyed	22-06-08	MT
Top Premarket Gainers	22-06-08	MT
Stealth BioTherapeutics Presents New SBT-272 Data Demonstrating Improvement in Upper Motor Neuron Function in ALS Disease Model at Keystone Neurodegeneration Symposium	22-06-08	CI
Stealth BioTherapeutics Gets European Medicines Agency Orphan Drug Designation for Elamipretide	22-05-31	MT
HC Wainwright Adjusts Stealth BioTherapeutics' Price Target to $1.50 from $4, Keeps Buy Rating	22-05-23	MT
Stealth BioTherapeutics Corp Announces Data from the Phase 2 ReCLAIM-2 Study of Elamipretide in Geographic Atrophy at the Clinical Trials at the Summit Meeting 2022	22-05-23	CI
Stealth BioTherapeutics Gets FDA's Orphan Drug Designation for Duchenne Muscular Dystrophy Drug Candidate; Shares Rise	22-05-12	MT
Wall Street Set for Losses Amid Inflation Worries; Weekly Jobless Claims Rise	22-05-12	MT
Top Premarket Gainers	22-05-12	MT

Chart Stealth BioTherapeutics Corp

Duration

Period

More charts

Company Profile

Stealth BioTherapeutics Corp is a clinical-stage biotechnology company. The Company is focused on the discovery, development and commercialization of therapies for diseases involving mitochondrial dysfunction. Its clinical product candidate, elamipretide, is a small peptide that targets and binds reversibly to cardiolipin, a structural element of mitochondria, stabilizing the inner mitochondrial membrane under conditions of oxidative stress. This mechanism of action has shown potential clinical benefit in both rare genetic and common age-related ophthalmic and cardiac diseases entailing mitochondrial dysfunction. The Company's second clinical product candidate include SBT-272, for rare neurological diseases involving mitochondrial dysfunction, with a preliminary focus on amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Its clinical product candidate also includes SBT-550 series for rare neurological indications, including Friedreich's ataxia (FRDA).

Sector

Biotechnology & Medical Research

More about the company

Sector Other Biotechnology & Medical Research

	1st Jan change	Capi.
MODERNA, INC.	+20.32%	42.68B
IQVIA HOLDINGS INC.	-1.80%	42.4B
LONZA GROUP AG	+45.21%	40.04B
CELLTRION, INC.	-6.20%	28.31B
ICON PUBLIC LIMITED COMPANY	+5.69%	24.94B
ALNYLAM PHARMACEUTICALS, INC.	-20.12%	18.96B
MEDPACE HOLDINGS, INC.	+30.34%	12.3B
CHARLES RIVER LABORATORIES INTERNATIONAL, INC.	-2.96%	11.95B
BIO-TECHNE CORPORATION	-3.89%	11.55B

Other Biotechnology & Medical Research