Item 5.07 Submission of Matters to a Vote of Security Holders.

The 2022 annual meeting of stockholders (the "Annual Meeting") of Tango Therapeutics, Inc. (the "Company") was held in a virtual-only format on June 8, 2022 at 10:00 a.m., Eastern Time via live webcast. Proxies were solicited pursuant to the Company's proxy statement filed on April 26, 2022 with the Securities and Exchange Commission under Section 14(a) of the Securities Exchange Act of 1934, as amended (the "Proxy Statement"). As of April 11, 2022, the record date for the Annual Meeting, the number of shares of the Company's common stock, $0.001 par value per share ("Common Stock"), outstanding and entitled to vote at the Annual Meeting was 87,712,630. The number of shares of Common Stock present or represented by valid proxy at the Annual Meeting was 81,740,796, representing 93.19% of the total number of shares of Common Stock entitled to vote at the Annual Meeting, thus establishing a quorum for the Annual Meeting. Shares present virtually during the Annual Meeting were considered shares of Common Stock represented in person at the Annual Meeting. Each share of Common Stock was entitled to one vote with respect to matters submitted to the Company's stockholders at the Annual Meeting.

At the Annual Meeting, the Company's stockholders were asked to vote on the following matters, which are described in detail in the Proxy Statement: (i) to elect two Class I director nominees to the Company's Board of Directors (the "Board"), each to hold office until the 2025 annual meeting of stockholders and until his or her successor is duly elected and qualified, or until his or her earlier resignation or removal ("Proposal 1"), and (ii) to ratify the selection of PricewaterhouseCoopers, LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2022 ("Proposal 2").

The voting results reported below are final.

Proposal 1 - Election of Directors

Lesley Ann Calhoun and Reid Huber were duly elected to the Company's Board as Class I directors. The results of the election were as follows:

CLASS I DIRECTOR NOMINEE FOR WITHHELD BROKER NON-VOTES Lesley Ann Calhoun 74,549,730 2,532,608 4,658,458 Reid Huber

               74,547,606 2,534,732    4,658,458

Proposal 2 - Ratify the Selection of Independent Registered Public Accounting Firm

The selection of PricewaterhouseCoopers, LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2022 was ratified. The results of the ratification were as follows:



   FOR     AGAINST ABSTAIN
81,737,938   400    2,458

No other matters were submitted to or voted on by the Company's stockholders at the Annual Meeting. --------------------------------------------------------------------------------

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