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    ALTME   NL0015000YE1

TME PHARMA N.V.

(ALTME)
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Real-time Estimate Tradegate  -  03:01 2022-08-15 am EDT
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NOXXON ANNOUNCES EUR2.375 MILLION FINANCING UNDER AGREEMENT WITH ATLAS

01/31/2022 | 08:18am EDT

Berlin, Germany - NOXXON Pharma N.V. (Euronext Growth Paris: ALNOX), a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announced that it has drawn down additional financing tranches from its financing agreement with Atlas Special Opportunities, LLC (ASO), for a total consideration of EUR2,375,000, and issued 2,419 convertible bonds (including 44 convertible bonds issued in relation to the transaction fee) with a nominal value of EUR 1,000 each. The remaining availability under the ASO facility extends the company's cash runway into December 2022.

The characteristics, terms and conditions of the ASO financing may be found in the April 23, 2020 and October 14, 2020 press releases. The expansion of the financing capacity and the dilutive potential have been published in the press release on January 3, 2022. NOXXON maintains an updated summary table of issued convertible bonds in the Investors' section of its website.

Contact:

NOXXON Pharma N.V.

Aram Mangasarian, Ph.D.

Chief Executive Officer

Tel: +49 (0) 30 726247 0

E: amangasarian@noxxon.com

Investor and Media

LifeSci Advisors

Guillaume van Renterghem

Tel: +41 (0) 76 735 01 31

E: gvanrenterghem@lifesciadvisors.com

NewCap

Arthur Rouille

Tel: +33 (0) 1 44 71 00 15

E: arouille@newcap.fr

About NOXXON

NOXXON's oncology-focused pipeline acts on the tumor microenvironment (TME) and the cancer immunity cycle by breaking the tumor protection barrier and blocking tumor repair. By neutralizing chemokines in the TME, NOXXON's approach works in combination with other forms of treatment to weaken tumor defenses against the immune system and enable greater therapeutic impact. NOXXON's lead program NOX-A12 has delivered final top-line data from a Keytruda combination trial in metastatic colorectal and pancreatic cancer patients published at the ESMO conference in September 2020 and in July 2021 the company announced its Phase 2 study, OPTIMUS, to further evaluate safety and efficacy of NOX-A12 in combination with Merck's Keytruda and two different chemotherapy regimens as second- line therapy in patients with metastatic pancreatic cancer. NOXXON is also studying NOX-A12 in brain cancer in combination with radiotherapy which has been granted orphan drug status in the US and EU for the treatment of certain brain cancers. GLORIA, a trial of NOX-A12 in combination with radiotherapy in newly diagnosed brain cancer patients who will not benefit clinically from standard chemotherapy has delivered interim data from the first two cohorts showing consistent tumor reductions and objective tumor responses. Additionally, GLORIA has been expanded to assess the benefit of NOX-A12 with other treatment combinations, radiotherapy + bevacizumab and radiotherapy + pembrolizumab. The company's second clinical-stage asset NOX-E36 is a Phase 2 TME asset targeting the innate immune system. NOXXON plans to test NOX-E36 in patients with solid tumors. Further information can be found at: www.noxxon.com.

Keytruda is a registered trademark of Merck Sharp & Dohme Corp.

Visit NOXXON on LinkedIn and Twitter.

About the GLORIA Study

GLORIA (NCT04121455) is NOXXON's dose-escalation, phase 1/2 study of NOX-A12 in combination with irradiation in first-line partially resected or unresected glioblastoma (brain cancer) patients with unmethylated MGMT promoter (resistant to standard chemotherapy). GLORIA further evaluates safety and efficacy of NOX-A12 three additional arms combining NOX-A12 with: A. radiotherapy in patients with complete tumor resection; B. radiotherapy and bevacizumab in patients with incomplete tumor resection; and C. radiotherapy and pembrolizumab in patients with incomplete tumor resection.

About the OPTIMUS Study

OPTIMUS (NCT04901741) is NOXXON's open-label two-arm phase 2 study of NOX-A12 combined with pembrolizumab and nanoliposomal irinotecan/5-FU/leucovorin or gemcitabine/nab-paclitaxel in microsatellite-stable metastatic pancreatic cancer patients.

Disclaimer

Certain statements in this communication contain formulations or terms referring to the future or future developments, as well as negations of such formulations or terms, or similar terminology. These are described as forward-looking statements. In addition, all information in this communication regarding planned or future results of business segments, financial indicators, developments of the financial situation or other financial or statistical data contains such forward-looking statements. The company cautions prospective investors not to rely on such forward-looking statements as certain prognoses of actual future events and developments. The company is neither responsible nor liable for updating such information, which only represents the state of affairs on the day of publication.

(C) 2022 Electronic News Publishing, source ENP Newswire

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Financials
Sales 2022 13,4 M 13,7 M 13,7 M
Net income 2022 - - -
Net Debt 2022 - - -
P/E ratio 2022 -
Yield 2022 -
Capitalization 3,96 M 4,06 M 4,06 M
Capi. / Sales 2022 0,30x
Capi. / Sales 2023 0,06x
Nbr of Employees 13
Free-Float 12,3%
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Number of Analysts 1
Last Close Price 4,70 €
Average target price 83,00 €
Spread / Average Target 1 666%
Managers and Directors
Aram Andrew Mangasarian Chief Business Officer
Bryan Jennings Chief Financial Officer & Statutory Director
Maurizio PetitBon Chairman-Supervisory Board
Cornelis Alexander Izeboud Member-Supervisory Board
Martine J. van Vugt Member-Supervisory Board
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