August 16, 2021

To whom it may concern:

Company Name

TOHO HOLDINGS CO., LTD.

Corporate

Atsushi Udoh, President and

Representative

Representative Director

(First Section of Tokyo Stock Exchange

Securities Code:8129)

Contact:

Makoto Kawamura, Director and General

Manager, Corporate Management

Division and Corporate Planning and

Investor Relations Department

(TEL: 81-3-6838-2803)

Notice Regarding Marketing Approvals for

1 Ingredient / 1 Product of Generic Drugs for KYOSOMIRAI PHARMA

TOHO HOLDINGS CO., LTD. (Headquarters: Tokyo; President and Representative Director: Atsushi Udoh) is pleased to announce that KYOSOMIRAI PHARMA CO., LTD. (Headquarters: Tokyo; President and Representative Director: Nobuaki Hosaka), the wholly-owned subsidiary involved in pharmaceuticals manufacture and sales business, has received approvals for marketing of 1 ingredient / 1 product of generic drugs today on August 16, 2021 as below.

Product list approved for marketing

Class

Product Name

Original Brand Name

Endothelin receptor antagonist

Ambrisentan Tablets 2.5mg

Volibris®Tablets

"KMP"

2.5mg

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Disclaimer

Toho Holdings Co. Ltd. published this content on 16 August 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 02 September 2021 09:01:01 UTC.