VAXIL BIO LTD. announced the initiation of the pre-clinical program for ImMucin™ in combination with the E-selectin binding polymer-based therapeutic, which Vaxil licensed for development and commercialization from BGN Technologies, the technology transfer company of Ben-Gurion University of the Negev, Israel (“BGU”). The pre-clinical program will be led by Prof. Ayelet David from BGU to assess the potential for ImMucin and the P-Esbp separately and in combination for the treatment of solid tumors including breast and ovarian cancer. P-Esbp was invented by Prof. Ayelet David, Head of the Drug Targeting and Nanomedicine Laboratory, Department of Clinical Biochemistry and Pharmacology, Prof. Gonen Ashkenasy from the Department of Chemistry and their joint PhD student, Yosi Shamay, all from the BGU. P-Esbp has been shown to interfere with E-selectin-mediated interactions, thus blocking leukocyte and cancer cells recruitment to inflamed and cancerous tissues, which reduced colonization of circulating cancer cells in secondary organs. In addition, it was also shown to inhibit leukocyte recruitment and inflammation in animal models of liver injury and atherosclerosis. These results combined demonstrate the promising therapeutic potential of E-selectin targeted therapy for inhibiting inflammation and arresting cancer disease progression as well as other diseases where inflammation plays a role. The work performed by Prof. David at BGU will be supported by the Company’s existing working capital.