Verseon presented new preclinical data on its novel class of precision oral anticoagulants (PROACs) at this week's BIO International Convention in Boston. Verseon's PROACs demonstrate a unique combination of efficacy with lower bleeding in preclinical testing. This suggests that PROACs may be uniquely positioned to address a significant need for prolonged combination therapy with antiplatelet drugs. Millions of patients worldwide could benefit from safe long-term co-dosing of an anticoagulant with one or more antiplatelet drugs (i.e. aspirin, PlavixTM) to prevent stroke or heart attack. However, current NOACs (novel oral anticoagulants) are not suitable for such therapy due to their high risk of bleeding. In multiple preclinical studies, Verseon demonstrated that PROACs prevent the formation of blood clots but do not disrupt platelet function. This provides a biological explanation for the significantly reduced bleeding of PROACs compared to NOACs. In addition, this enables PROACs to more precisely influence the coagulation cascade, making them more suitable for co-administration with antiplatelet drugs.