Vigil Neuroscience, Inc. announced the appointment of Christopher J. Silber, M.D. as Chief Medical Officer. Dr. Silber brings over 30 years of biopharmaceutical industry experience and a track record of clinical and regulatory success developing novel therapeutics in neuroscience. Dr. Silber joins Vigil from Nocion Therapeutics, where he was Chief Medical Officer and led the clinical strategy for the company's small molecule platform, including development of NTX-1175, a new chemical entity for cough indications.

Prior to Nocion, he served as Senior Vice President, Clinical Development at Sage Therapeutics, where he led clinical development efforts for the portfolio, supporting the U.S. Food and Drug Administration (FDA) approval of ZULRESSO for the treatment of postpartum depression, zuranolone development for major depressive disorder and postpartum depression, and progression of the early neurology therapeutics pipeline. Previously at Agilis Biotherapeutics, Dr. Silber served as Chief Medical Officer where he oversaw the gene therapy pipeline focused on rare diseases of the CNS, including work contributing to the subsequent approval of Upstaza for aromatic L-amino acid decarboxylase (AADC) deficiency. He also held positions of increasing responsibilities at Lundbeck, Takeda, Hospira and Abbott Laboratories.

Dr. Silber earned his B.A. in Psychology from Tufts University and his M.D. at Jacobs School of Medicine and Biomedical Sciences at the University of Buffalo.