XBiotech Inc. announced the appointment of William Levis, MD to its Scientific Advisory Board (SAB). Dr. Levis will work with XBiotech to help advance the clinical program in dermatology, including Hidradenitis Suppurativa (HS). Topline results from the Phase 2 study evaluating XBiotech’s True Human antibody, MABp1, as a treatment for HS were announced earlier this year. The study met its primary endpoint, demonstrating significant improvement of HS patients compared to control after 12 weeks of therapy (Response rate of 60% vs 10%, respectively (p=0.035)). Other current product candidates in the Company’s dermatology program, all of which have completed phase 2 clinical studies, include Psoriasis, Acne and Pyoderma Gangrenosum. IL-1a drives chronic sterile inflammation in the skin. IL-1a from keratinocytes and inflammatory cells present in skin lesions makes it a prominent target for therapy. The strong safety profile targeting IL-1? also makes it an ideal treatment for dermatological conditions. Dr. Levis serves as Chairman of the Foundation for Global Skin Health Strategies and Lifetime Professor of Dermatology, Rockefeller University. He is presently Attending Physician, New York Hansen’s Disease Program, Bellevue Hospital Center, New York, NY.