Xynomic Pharma and Bison Capital Acquisition Corp. jointly announced that China, Spain and Poland authorities have approved Xynomic's application to conduct potentially pivotal Phase 3 trial using Xynomic's abexinostat, in combination with pazopanib, in patients with renal cell carcinoma (RCC). Xynomic plans to initiate this trial in China, Spain, Poland and additional European countries in the first half of 2019. The same trial is currently ongoing in the United States and South Korea. According to a June 2018 research report by Grand View Research, RCC accounts for 1.8% of total adult malignancies globally and 3.4% of all new cancer cases in the United States. The global RCC pharmaceuticals market size is projected to reach USD 4.6 billion in 2019. In addition, the Independent Ethics Committee at the Cancer Hospital Chinese Academy of Medical Sciences in Beijing has approved Xynomic's application to conduct two potentially pivotal Phase 2 trials, one to test abexinostat as a third-line mono therapy against diffuse large B-cell lymphoma (DLBCL) and the other as a third-line mono therapy against follicular lymphoma (FL). According to Chinese Medical Association'sChinese Society of Hematology, DLBCL and FL are the most prevalent and second most prevalent non-Hodgkin's lymphoma subtype, respectively, in China.