Zenith Epigenetics Ltd. announced the dosing of first patient with a triple combination of ZEN-3694 + Merck's immune check point inhibitor, KEYTRUDA, + Pfizer's androgen receptor signaling inhibitor (ARSI), XTANDI, in a University of California, San Francisco (UCSF) investigator led metastatic castration resistant prostate cancer (mCRPC) Phase 2 clinical trial. ZEN-3694, the Company's lead therapeutic compound, is being developed for epigenetic combination therapies in multiple oncology indications. This clinical trial will evaluate the aforementioned triple combination therapy in mCRPC patients that have become resistant to 1st a 1 line ARSI therapy. These patients have a very poor prognosis and have a significant need for non-chemotherapies. This study is being supported in part by a research grant from the Investigator-Initiated Studies Program of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co. Inc.