William Worthen

Trimedyne, Inc. engages in the development, manufacturing, and marketing of lasers and disposable fiber optic delivery devices for use in medical applications. Its products include laser systems. lithotripsy fibers, urology fibers, orthopedic fibers, and laser needles. The company was founded by Marvin P. Loeb in 1980 and is headquartered in Irvine, CA.

Alsius Corp. develops advanced intravascular temperature management therapies for critically ill patients in the intensive care and surgical setting. Its thermal regulation products allow caregivers the ability to manage core body temperature. The company is headquartered in Irvine, CA

NeurOptics, Inc. provides neurological patient care services. It offers npi-100 pupillometer, an hand-held and cordless device that removes subjectivity in the measurement of pupil size and the pupillary light reflex. The company was founded by Kamran Siminou and is headquartered in Irvine, CA.

Branchpoint Technologies, Inc. provides health care services. It develops pressure management platforms for medical applications. The company was founded by Kevin Hughes and is headquartered in Irvine, CA.

Part of Boston Scientific Corp., InterTherapy, Inc. is a company that manufactures and markets ultrasound imaging systems. The company is based in Santa Ana, CA. The company was founded by Paul J. Zalesky. InterTherapy was acquired by Cardiovascular Imaging Systems, Inc. on September 21, 1992 for $16.70 million.

Part of Kimberly-Clark Corp., Neuro Navigational Corp develops and markets fiber-optic imaging technology. The company is based in Costa Mesa, CA. Neuro Navigational was acquired by Ballard Medical Products on March 04, 1997.

The Group's principal activity is to develops, manufactures, markets and sells, proprietary catheter-based products for rapid cooling and temperature control of patients with severe neuronal injury, including those who have suffered stroke, traumatic brain injury and cardiac arrest. Its products consist of the CoolGard and Thermogard systems and four families of single-use catheters-Cool line, Icy, Fortius and Quattro. The CoolGard and Thermogard systems are computer-controlled temperature regulation systems that circulate cool or warm saline in a closed-loop circuit through balloons that surround their catheters. The Group operating through US, Austria , Germany, France and Rest of Europe.

Gardia Medical specializes in the development of catheter-based delivery systems that easily integrate with the standard workflow of stenting and other cardiovascular intervention procedures. It offers wire-independent distal filtration Embolic Protection Device (EPD), compatible with standard guide wires. The company was founded by Benjamin Spenser and Uri Rosenshein in 2006 and is headquartered in Hadera, Israel.