10x Genomics, Inc. announced the commercial availability of its Visium HD Spatial Gene Expression product. This assay enables researchers to measure the whole transcriptome from FFPE tissue sections at single cell-scale resolution. Combining the power of whole transcriptome spatial discovery with histological insights, Visium HD enables comprehensive characterization of FFPE tissue samples.

Visium HD offers: Whole transcriptome spatial discovery power at single cell scale: Use next-generation slide architecture, which provides transcript data in 2 x 2 µm barcoded squares without gaps, to resolve fine anatomical structures and map cell types and states at single cell-scale resolution. Best-in-class sequencing-based spatial transcriptomics data: Map gene expression with precision and high confidence using a simple and robust workflow exclusively available on Visium CytAssist. FFPE compatibility: Generate powerful data from human or mouse FFPE samples, including archived blocks or pre-sectioned slides, using a universal sample preparation protocol.

Enhanced histology: Integrate H&E or IF images with high-resolution spatial transcriptomics from the same tissue section. Easy-to-use analysis and visualization tools: Seamlessly combine histological and gene expression data using updated versions of Space Ranger and Loupe Browser to enable intuitive data exploration and accelerate discovery.