On March 14, 2024, Andrew Powell, a member of the board of directors of Aclaris Therapeutics, Inc. notified the Company of his intent to resign as a member of the Board, effective as of the date of the Company?s 2024 Annual Meeting of Stockholders, which is expected to be held on June 6, 2024 Mr. Powell?s resignation from the Board was not the result of any disagreement with the Company on any matter relating to the Company?s operations, policies or practices. Also on March 14, 2024, Bryan Reasons, a member of the Board, notified the Company that he will not stand for re-election as a director of the Company upon the expiration of his current term, which expires at the Annual Meeting. Mr. Reasons?

refusal to stand for re-election was not the result of any disagreement with the Company on any matter relating to the Company?s operations, policies or practices.