Item 1.01. Entry into a Material Definitive Agreement.

On June 15, 2022, Adaptimmune Therapeutics plc (the "Company" or "Adaptimmune") entered into a Deed of Surrender of Part with MEPC Milton Park No. 1 Limited and MEPC Milton Park No. 2 Limited ("MEPC") through which the Company surrendered part of the property known as 39 Innovation Drive, Milton Park, Oxfordshire, U.K. ("39 Innovation Drive") to MEPC (the "Deed of Surrender") so that MEPC could grant a lease to The Electricity Network Company Limited on June 15, 2022 in connection with the installation of an electricity substation to serve Adaptimmune's facility at 39 Innovation Drive (the "Substation Lease"). On June 15, 2022, the Company also entered into a Deed of Variation with MEPC of the lease of 39 Innovation Drive dated February 28, 2018 between MEPC and the Company (the "39 Innovation Drive Lease") to implement variations to the 39 Innovation Drive Lease so that it is subject to rights granted in the Substation Lease related to the laying and maintenance of cables for the electricity substation (the "Deed of Variation"). All other terms of the 39 Innovation Drive Lease remain unchanged.

The foregoing descriptions of the Deed of Surrender and the Deed of Variation are qualified in their entirety by reference to the full text of such documents, copies of which are filed herewith as Exhibit 10.1 and Exhibit 10.2, respectively, and incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.



(d)  Exhibits.

Exhibit No.                           Description of Exhibit

   10.1          Deed of Surrender of Part dated June 15, 2022, between MEPC Milton
               Park No 1 Limited and MEPC Milton Park No. 2 Limited and Adaptimmune
               Limited relating to a lease of 39 Innovation Drive, Milton Park.

   10.2          Deed of Variation dated June 15, 2022, between MEPC Milton Park No
               1 Limited and MEPC Milton Park No. 2 Limited and Adaptimmune Limited
               relating to a lease of 39 Innovation Drive, Milton Park.

    104        Cover Page Interactive Date File (embedded within the Inline XBRL
               document)

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