Item 8.01 Other Events.




As previously disclosed, TCR2 Therapeutics Inc. ("TCR2") entered into an
Agreement and Plan of Merger (the "Merger Agreement") with Adaptimmune
Therapeutics plc ("Adaptimmune") and CM Merger Sub, Inc., a Delaware corporation
("Merger Sub"), pursuant to which Merger Sub will be merged with and into TCR2
(the "Merger"), with TCR2 surviving the merger as a wholly-owned direct
subsidiary of CM Intermediate Sub II, Inc., a Delaware corporation and
wholly-owned subsidiary of Adaptimmune ("CM Intermediate"). On April 20, 2023,
each of Adaptimmune and TCR2 filed the definitive version of the joint proxy
statement with the United States Securities and Exchange Commission (the "SEC")
in connection with the Merger (the "Proxy Statement").



Since the filing of the Proxy Statement, two complaints have been filed by
purported TCR2 stockholders as individual actions against TCR2 and the members
of its Board of Directors. One complaint has been filed in the United States
District Court for the Southern District of New York, captioned Scott v. TCR2
Therapeutics, Inc. et al., Case No. 1:23-cv-3763 (filed May 4, 2023), and one
complaint has been filed in the United States District Court for the District of
Delaware, captioned Thompson v. TCR2 Therapeutics, Inc. et al., Case
No. 1:23-cv-503 (filed May 8, 2023). The foregoing complaints are referred

to as
the "Merger Actions."



The Merger Actions allege that the Proxy Statement misrepresents and/or omits
certain purportedly material information. The Merger Actions assert claims for
violation of Section 14(a) of the Securities Exchange Act of 1934, as amended
(the "Exchange Act"), and Rule 14a-9 promulgated thereunder against TCR2and its
Board of Directors, and violations of Section 20(a) of the Exchange Act against
TCR2's Board of Directors.



Additionally, on April 20, 2023, April 21, 2023, April 26, 2023, May 5, 2023,
May 12, 2023, May 15, 2023, and May 17, 2023, five purported TCR2 stockholders
and three purported Adaptimmune shareholders sent demand letters alleging
similar insufficiencies in the disclosures in the Proxy Statement in violation
of Section 14(a) of the Exchange Act and Rule 14a-9 promulgated thereunder, and
Section 20(a) of the Exchange Act (such letters, the "Demands" and collectively
with the Merger Actions, the "Litigation Matters").



The plaintiffs in the Litigation Matters seek various remedies including, among
other things, an order enjoining the consummation of the Merger, requiring the
defendants to file an amended Proxy Statement, rescinding the Merger in the
event it is consummated or granting rescissory damages, and awarding costs of
the action, including plaintiff's attorneys' fees and experts' fees, and other
relief the court may deem just and proper.



TCR2 and Adaptimmune believe that the claims asserted in the Litigation Matters
are without merit. TCR2 and Adaptimmune deny that any further disclosure beyond
that already contained in the Proxy Statement is required under applicable law
to supplement the Proxy Statement, as claimed in the Litigation Matters.
Nonetheless, to moot these purported stockholders' unmeritorious claims, avoid
the risk that litigation may delay or otherwise adversely affect the
consummation of the Merger and to minimize the expense of defending against the
Complaints and the Demands, TCR2 and Adaptimmune are making the following
supplemental disclosures to the Proxy Statement. Nothing in this Current Report
on Form 8-K shall be deemed an admission of the legal necessity or materiality
under applicable laws of any of the supplemental disclosures set forth herein.
To the contrary, TCR2 and Adaptimmune specifically deny all allegations in the
Litigation Matters that any additional disclosure was or is required.



Supplemental Disclosures



This supplemental information to the Proxy Statement should be read in
conjunction with the Proxy Statement, which should be read in its entirety. All
page references in the information below are to pages in the Proxy Statement,
and all terms used but not defined below shall have the meanings set forth in
the Proxy Statement. To the extent the following information differs from or
conflicts with the information contained in the Proxy Statement, the information
set forth below shall be deemed to supersede the respective information in the
Proxy Statement. New text within the amended and supplemented language from the
Proxy Statement is indicated in bold and underlined text (e.g., bold, underlined
text), and deleted text within the amended and supplemented language from the
Definitive Proxy Statement is indicated in bold and strikethrough text (e.g.,
bold, strikethrough text).








The disclosure in the section entitled "Background of the Merger," beginning on page 55 of the Proxy Statement, is hereby amended and supplemented as follows:

The following text is added to the second sentence of the fourth full paragraph on page 66 of the Proxy Statement:





Also, on February 10, 2023, following negotiation between the parties and after
hearing from Party G and concluding that Party H was uninterested in pursuing
any discussion, TCR2 and Adaptimmune entered into the February 10 NDA, which
included customary non-disclosure provisions and mutual standstill provisions
that prohibited either party, for three months from the date of the agreement,
from offering to acquire or acquiring the other party, and from taking certain
other actions, including soliciting proxies, without the prior written consent
of the other party. The confidentiality agreement provided for the termination
of the standstill provision on customary terms three-month standstill provision
in the February 10 NDA terminates: (i) immediately upon the public announcement
that either TCR2or Adaptimmune has entered into a definitive agreement with a
third party for a business combination transaction or the entry into a
definitive agreement for the strategic transaction between TCR2 and Adaptimmune;
or (ii) 11 business days following the commencement by any person of a cash
tender offer seeking to acquire beneficial ownership of more than 50% of TCR2's
or Adaptimmune's outstanding voting securities, as applicable, unless that
party's Board of Directors publicly recommended to its respective stockholders
that such tender offer be rejected.



The following text is added after the first full paragraph on page 71 of the Proxy Statement:





On May 18, 2023, the TCR2Board held a meeting at which members of TCR2 senior
management and representatives of Goodwin were present. At this meeting, TCR2
senior management provided an update to the TCR2 Board about certain information
sourcing and calculation errors (as summarized in this joint proxy
statement/prospectus under the section titled "The Merger - Opinion of TCR2's
Financial Advisor") in Piper Sandler's March 5, 2023 presentation to the
TCR2Board that impacted Piper Sandler's analyses and that Piper Sandler had
identified after March 5, 2023 and after the joint proxy statement/prospectus
was filed on April 20, 2023, and the ongoing review of those errors.
Representatives of Goodwin reviewed with the members of the TCR2 Board their
fiduciary duties. The TCR2 Board discussed such matters and determined to
reconvene to further discuss them with representatives of Piper Sandler.



On May 20, 2023, the TCR2 Board held a meeting at which members of TCR2 senior
management and representatives of Goodwin were present. TCR2 senior management
updated the TCR2 Board on their discussions with representatives of Piper
Sandler and their review of the information sourcing and calculation errors that
Piper Sandler had identified in its March 5, 2023 presentation. Representatives
of Goodwin next reviewed with the members of the TCR2 Board their fiduciary
duties. Representatives of Piper Sandler then joined the meeting and reviewed
with the TCR2 Board those information sourcing and calculation errors (as
summarized in this joint proxy statement/prospectus under the section titled
"The Merger - Opinion of TCR2's Financial Advisor") in Piper Sandler's March 5,
2023 presentation to the TCR2 Board that impacted Piper Sandler's analyses and
that Piper Sandler had identified after March 5, 2023 and after the definitive
version of the joint proxy statement/prospectus was filed with the SEC on
April 20, 2023. Representatives of Piper Sandler informed the TCR2 Board that,
after preliminarily identifying certain errors in its March 5, 2023 analyses, in
addition to the members of the Piper Sandler team that advised on the potential
business combination reviewing its analyses in the March 5, 2023 presentation to
the TCR2 Board, Piper Sandler also had assembled a separate review team, whose
members were not part of the original transaction team advising on the potential
business combination with Adaptimmune, to review its analyses contained in the
March 5, 2023 presentation to the TCR2 Board under the direction and oversight
of additional members of the Piper Sandler opinion committee senior leadership,
who themselves were not involved on the transaction team advising on the
potential business combination with Adaptimmune. Representatives of Piper
Sandler then discussed with the TCR2 Board the results of that supplemental
review, including certain corrections to Piper Sandler's prior analyses
resulting therefrom, and the impact of those corrections on its analyses.
Representatives of Piper Sandler informed the TCR2 Board that these corrections
had no impact on Piper Sandler's fairness opinion conclusion, as previously
provided to the Board on March 5, 2023. During this discussion, members of the
TCR2 Board asked questions of the representatives of Piper Sandler. Following
this discussion, the representatives of Piper Sandler left the meeting. TCR2
senior management then discussed their meetings with representatives of Piper
Sandler and their review of the corrections to Piper Sandler's analyses. The
TCR2 Board further discussed the corrections to Piper Sandler's March 5, 2023
analyses, the fact that Piper Sandler had assembled a separate review team whose
members were not part of the original transaction team advising on the potential
business combination with Adaptimmune to review the March 5 analyses, including
the Piper Sandler opinion committee senior leadership, and the fact that TCR2
senior management had met with representatives of Piper Sandler and reviewed the
corrections to Piper Sandler's analyses. The TCR2 Board also discussed that
there were a number of reasons why the TCR2 Board approved and recommended the
Merger in addition to the Piper Sandler fairness opinion, including the factors
summarized in this joint proxy statement/prospectus in the section entitled
"TCR2's Reasons for the Merger; Recommendation of the TCR2 Board that TCR2
Stockholders Approve the Merger Proposal." On the basis of all of the foregoing
considerations, the TCR2 Board determined that it was reasonable to rely on
Piper Sandler's corrected analyses and Piper Sandler's determination that the
corrections had no impact on the fairness opinion conclusion previously provided
to the TCR2 Board on March 5, 2023. The TCR2 Board further determined that, had
the TCR2 Board been aware of Piper Sandler's corrected financial analyses on
March 5, 2023, those corrected analyses would not have changed the TCR2 Board's
determination that the terms of the merger and the other transactions
contemplated by the merger agreement were advisable, fair to, and in the best
interests of TCR2 and TCR2 stockholders for the reasons discussed in the section
entitled "TCR2's Reasons for the Merger; Recommendation of the TCR2 Board that
TCR2 Stockholders Approve the Merger Proposal." The TCR2 Board also determined
that, had representatives of Piper Sandler presented and the TCR2 Board
considered the corrected analyses on March 5, 2023, the TCR2 Board would not
have made a different recommendation to the TCR2 stockholders concerning the
merger.








The disclosure in the section entitled "Opinion of Adaptimmune's Financial Advisor," beginning on page 75 of the Proxy Statement, is hereby amended and supplemented as follows:

The disclosure under the subheading "Selected Publicly Traded Companies Analyses" is hereby amended and supplemented by adding the following text to the first sentence of the fourth full paragraph on page 79 of the Proxy Statement:


Although the Adaptimmune selected companies and the TCR2 selected companies were
used for comparison purposes, none of those companies is directly comparable to
Adaptimmune or TCR2 nor, except as otherwise disclosed, were individual
enterprise values derived from the Adaptimmune selected companies and the TCR2
selected companies independently determinative of the results of the selected
publicly traded companies analyses described above.



The disclosure under the subheading "Selected Precedent Transactions Analysis"
is hereby amended and supplemented by adding the following text to the first
sentence of the third full paragraph on Page 80 of the Proxy Statement:



Although the selected transactions were used for comparison purposes, none of
those transactions is directly comparable to the merger, and none of the
companies involved in those transactions is directly comparable to TCR2, nor,
except as otherwise disclosed, were individual enterprise values derived from
the selected transactions independently determinative of the results of the
selected precedent transactions analysis described above.


The disclosure under the subheading "Discounted Cash Flow Analyses-Adaptimmune"
is hereby amended and supplemented by modifying the third sentence of the fifth
full paragraph on page 80 of the Proxy Statement as follows:



TD Cowen calculated implied terminal values for Adaptimmune by applying to
Adaptimmune's estimated unlevered, after-tax free cash flows for the fiscal year
ending December 31, 2031 a selected range of perpetuity growth rates of (10)% to
3% selected based on TD Cowen's professional judgment.



The disclosure under the subheading "Discounted Cash Flow Analyses-Adaptimmune"
is hereby further amended and supplemented by adding the following text to the
fourth sentence of the fifth full paragraph on page 80 of the Proxy Statement:



The present values (as of May 31, 2023) of the cash flows and terminal values were then calculated using a selected range of discount rates of 12% to 16% derived from a weighted average cost of capital calculation.

The disclosure under the subheading "Discounted Cash Flow Analyses-TCR2" is hereby amended and supplemented by modifying the third sentence of the sixth full paragraph on page 80 of the Proxy Statement as follows:

TD Cowen calculated implied terminal values for TCR2 by applying to TCR2's estimated unlevered, after-tax free cash flows for the fiscal year ending December 31, 2043 a selected range of perpetuity growth rates of (33)% to (10)% selected based on TD Cowen's professional judgment.

The disclosure under the subheading "Discounted Cash Flow Analyses-TCR2" is hereby further amended and supplemented by adding the following text to the fourth sentence of the sixth full paragraph on page 80 of the Proxy Statement:

The present values (as of May 31, 2023) of the cash flows and terminal values were then calculated using a selected range of discount rates of 15% to 20% derived from a weighted average cost of capital calculation.





The disclosure under the subheading "Certain Additional Information" is hereby
amended and supplemented by adding the following text to the third bullet point
of the first paragraph on Page 81 of the Proxy Statement:



· the implied premiums paid or proposed to be paid in 19 selected acquisition

transactions involving biotechnology target companies announced during the

two-year period ended March 3, 2023 with approximate implied transaction values

of less than $500 million; applying a selected range of implied premiums of

approximately 45% to 175% (reflecting the overall 25th and 75th percentile

implied premiums derived from such transactions based on the closing stock

prices of the target companies involved in such transactions one trading day

prior to public announcement of such transactions) to the closing price of TCR2

Common Stock on March 3, 2023 of $1.21 per share indicated an approximate

implied equity value reference range for TCR2 of $1.80 to $3.35 per share

The disclosure under the heading "Opinion of TCR2's Financial Advisor," beginning on page 90 of the Proxy Statement, is hereby amended as follows:

The following text is added to the fourth full paragraph on page 91 of the Proxy Statement:





Unless the context indicates otherwise, for purposes of the financial analyses
described below, Piper Sandler calculated (i) enterprise value (defined as the
relevant company's common equity value, plus book value of preferred stock, plus
debt, less cash and cash equivalents, and less short and long term marketable
securities ("net debt"), plus, where applicable, book value of non-controlling
interests), for TCR2, Adaptimmune and each selected public company based on
(a) the market value of the relevant company's diluted common equity, using
closing stock prices as of March 3, 2023, calculated using the treasury stock
method ("TSM") and (b) the relevant company's net debt as of such company's most
recently reported quarter end, except in the case of each of TCR2 and
Adaptimmune, for which Piper Sandler used estimated net debt as of March 31,
2023 (which estimates were net cash of approximately $120 million and
approximately $165 million, respectively, as of such date) and (ii) implied per
share values for each of TCR2 and Adaptimmune, using diluted shares, calculated
using TSM as of March 4, 2023 (based on the closing price per share of TCR2
Common Stock and the closing price per Adaptimmune ADS as of March 3, 2023, such
diluted shares were approximately 40.8 million and 187.5 million, respectively).








The disclosure under the subheading "Selected Public Companies Analyses - TCR2 - Standalone" is hereby amended and supplemented by adding the following text after the third table on page 92 of the Proxy Statement:

Subsequent to the March 5, 2023 TCR2 Board meeting and after the definitive version of the joint proxy statement/prospectus was filed with the SEC on April 20, 2023, Piper Sandler discovered certain information sourcing and calculation errors which impacted the foregoing selected public companies analysis presented to the TCR2 Board on March 5, 2023.





This discovery did not result in any change to Piper Sandler's fairness opinion
or its conclusion. Piper Sandler did, however, provide the TCR2 Board on May 20,
2023 with a revised selected public companies analysis for TCR2 on a standalone
basis as if such corrections had been made in the materials presented to the
TCR2 Board on March 5, 2023. This revised analysis indicated the maximum, 75th
percentile, mean, median, 25th percentile and minimum equity values and
enterprise values for the selected public companies set forth below:



($ in millions)
                  Equity Value       Enterprise Value
Maximum           $         237     $               (4 )
75th Percentile   $         129     $              (61 )
Mean              $         115     $              (94 )
Median            $         109     $             (104 )
25th Percentile   $          70     $             (137 )
Minimum           $          44     $             (156 )










Piper Sandler then derived a range of implied enterprise values for TCR2 as if
such corrections had been made in the materials presented to the TCR2 Board on
March 5, 2023, based on the foregoing revised implied enterprise value ranges
for the selected public companies. Piper Sandler then adjusted for estimated net
cash for TCR2 as of March 31, 2023 and used the diluted share information
described above to calculate an implied value range of TCR2 Common Stock per
share. This analysis did not account for any assumed additional cash needs of
TCR2 to fund its business plan. Based on the minimum, 25th percentile, median,
mean, 75th percentile and maximum implied equity values for TCR2, Piper Sandler
calculated the following corresponding implied value range for TCR2 Common

Stock
per share:



                     Minimum    25th Percentile     Median           Mean  

     75th Percentile        Maximum
Implied TCR2 Per
Share Value                NM                NM   $      0.41     $     0.66     $           1.45     $      2.81

The disclosure under the subheading "Selected Public Companies Analyses - Adaptimmune - Standalone" is hereby amended and supplemented by adding the following text after the third table on page 93 of the Proxy Statement:

Subsequent to the March 5, 2023 TCR2 Board meeting and after the definitive version of the joint proxy statement/prospectus was filed with the SEC on April 20, 2023, Piper Sandler discovered certain information sourcing and calculation errors which impacted the foregoing selected public companies analysis presented to the TCR2 Board on March 5, 2023.





This discovery did not result in any change to Piper Sandler's fairness opinion
or its conclusion. Piper Sandler did, however, provide the TCR2Board on May 20,
2023 with a revised selected public companies analysis for Adaptimmune on a
standalone basis as if such corrections had been made in the materials presented
to the TCR2 Board on March 5, 2023. This revised analysis indicated the maximum,
75th percentile, mean, median, 25th percentile and minimum equity values and
enterprise values for the selected public companies set forth below:



($ in millions)
                  Equity Value       Enterprise Value
Maximum           $       1,666     $            1,141
75th Percentile   $       1,422     $              997
Mean              $         783     $              480
Median            $         353     $              107
25th Percentile   $         336     $              101
Minimum           $         137     $               53




Piper Sandler then derived a range of implied enterprise values for Adaptimmune
as if such corrections had been made in the materials presented to the TCR2
Board on March 5, 2023 based on the foregoing revised implied equity values and
enterprise value ranges for the selected public companies. Piper Sandler then
adjusted for estimated net cash for Adaptimmune as of March 31, 2023 and used
the diluted share information described above to calculate an implied value
range of Adaptimmune per ADS. This analysis did not account for any assumed
additional cash needs of Adaptimmune to fund its business plan. Based on the
minimum, 25th percentile, median, mean, 75thpercentile and maximum implied
equity values for Adaptimmune, Piper Sandler calculated the following
corresponding implied value range for Adaptimmune per ADS, which Piper Sandler
provided to the TCR2 Board on May 20, 2023:



                     Minimum       25th Percentile        Median           Mean        75th Percentile        Maximum
Implied
Adaptimmune Per
ADS Value          $      1.17     $           1.43     $      1.46     $     3.37     $           6.02     $      6.75

The disclosure under the subheading "Selected Public Companies Analyses - Implied Exchange Ratio Reference Ranges" is hereby amended and supplemented by adding the following text after the last table on page 93 of the Proxy Statement:

Subsequent to the March 5, 2023 TCR2 Board meeting and after the definitive version of the joint proxy statement/prospectus was filed with the SEC on April 20, 2023, Piper Sandler discovered certain information sourcing and calculation errors which impacted the foregoing selected public companies analyses presented to the TCR2 Board on March 5, 2023, as described above.





This discovery did not result in any change to Piper Sandler's fairness opinion
or its conclusion. Piper Sandler did, however, provide the TCR2 Board on May 20,
2023 with the revised implied exchange ratio reference ranges set forth below,
based on the revised public companies analyses for each of TCR2 and Adaptimmune
on standalone bases described above as if such corrections had been made in the
materials presented to the TCR2 Board on March 5, 2023, as compared to the

Exchange Ratio:



 Minimum       Median         Mean         Maximum       Exchange Ratio
  0.0000x       0.2831x       0.1957x       2.3942x           1.5117x



The disclosure under the subheading "Discounted Cash Flow Analyses - TCR2 - Standalone" is hereby amended and supplemented by adding the following text to the first sentence of the first full paragraph on page 94 of the Proxy Statement:





Using a discounted cash flow analysis, Piper Sandler calculated an estimated
range of theoretical enterprise values for TCR2 based on the net present value
of (i) projected unlevered after-tax free cash flows from April 1, 2023 to
December 31, 2043 (which reflected estimated net operating loss generation and
usage, as well as estimated research and development tax credits usage, over
such period), discounted back to April 1, 2023, and (ii) a projected terminal
value at December 31, 2043 calculated using a range of perpetuity growth rates
ranging from (1.0)% to 1.0% selected by Piper Sandler based on its professional
judgment, discounted back to April 1, 2023.



The disclosure under the subheading "Discounted Cash Flow Analyses - TCR2 - Standalone" is hereby amended and supplemented by adding the following text after table on page 94 of the Proxy Statement:

Subsequent to the March 5, 2023 TCR2 Board meeting and after the definitive version of the joint proxy statement/prospectus was filed with the SEC on April 20, 2023, Piper Sandler discovered certain information sourcing and calculation errors which impacted the foregoing discounted cash flow analysis presented to the TCR2 Board on March 5, 2023.





This discovery did not result in any change to Piper Sandler's fairness opinion
or its conclusion. Piper Sandler did, however, provide the TCR2 Board on May 20,
2023 with a revised discounted cash flow analysis for TCR2 on a standalone basis
as if such corrections had been made in the materials presented to the TCR2
Board on March 5, 2023. This revised analysis indicated the minimum, 25th
percentile, median, mean, 75th percentile and maximum implied value for TCR2
Common Stock per share set forth below:



                     Minimum       25th Percentile        Median           Mean        75th Percentile        Maximum
Implied TCR2 Per
Share Value        $      0.82     $           1.24     $      1.70     $     1.74     $           2.22     $      2.80










The disclosure under the subheading "Discounted Cash Flow Analyses - Adaptimmune
- Standalone" is hereby amended and supplemented by adding the following text to
the first sentence of the third full paragraph on page 94 of the Proxy
Statement:



Using a discounted cash flow analysis, Piper Sandler calculated an estimated
range of theoretical enterprise values for Adaptimmune based on the net present
value of (i) projected unlevered after-tax free cash flows from April 1, 2023 to
December 31, 2031, discounted back to April 1, 2023, and (ii) a projected
terminal value at December 31, 2031 calculated using a range of perpetuity
growth rates ranging from 0.0% to 2.0% selected by Piper Sandler based on its
professional judgment, discounted back to April 1, 2023.



The disclosure under the subheading "Discounted Cash Flow Analyses - Adaptimmune
- Standalone" is hereby amended and supplemented by adding the following text
after the first table on page 95 of the Proxy Statement:



Subsequent to the March 5, 2023 TCR2 Board meeting and after the definitive version of the joint proxy statement/prospectus was filed with the SEC on April 20, 2023, Piper Sandler discovered certain information sourcing and calculation errors which impacted the foregoing discounted cash flow analysis presented to the TCR2 Board on March 5, 2023.





This discovery did not result in any change to Piper Sandler's fairness opinion
or its conclusion. Piper Sandler did, however, provide the TCR2 Board on May 20,
2023 with a revised discounted cash flow analysis for Adaptimmune on a
standalone basis as if such corrections had been made in the materials presented
to the TCR2 Board on March 5, 2023. This revised analysis indicated the minimum,
25th percentile, median, mean, 75th percentile and maximum implied value for
Adaptimmune per ADS set forth below:



                     Minimum       25th Percentile        Median           Mean        75th Percentile        Maximum
Implied
Adaptimmune Per
ADS Value          $      0.51     $           0.85     $      1.06     $     1.09     $           1.29     $      1.80




The disclosure under the subheading "Discounted Cash Flow Analyses - Implied
Exchange Ratio Reference Ranges" is hereby amended and supplemented by adding
the following text after the second table on page 95 of the Proxy Statement:



Subsequent to the March 5, 2023 TCR2 Board meeting and after the definitive . . .

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