Item 5.07Submission of Matters to a Vote of Security Holders

The Annual Meeting of Stockholders of the Company was held on March 16, 2022 (the "Annual Meeting"). A total of 266,837,916 shares of Common Stock, representing approximately 88.84% of the shares outstanding, were represented at the Annual Meeting. The voting results for each item of business presented at the Annual Meeting, as certified by the Company's independent inspector of elections, are set forth below:

Proposal No. 1 The election of three (3) directors for a term of three years. The


               individuals listed below received the affirmative vote of a
               majority of the votes cast by the shares present in person or
               represented by proxy and entitled to vote at the Annual Meeting
               and were each elected to serve a three-year term.



           Name                 For      Against   Abstain Broker Non-Vote
Hans E. Bishop              219,566,395 26,056,611 444,401   20,770,508

Otis W. Brawley, M.D. 241,120,057 4,497,367 449,983 20,770,508 Mikael Dolsten, M.D., Ph.D. 234,934,495 10,673,089 459,823 20,770,508

Directors Mala Anand, Koh Boon Hwee, Heidi Kunz, Michael R. McMullen, Daniel K. Podolsky, M.D., Sue H. Rataj, George A. Scangos, Ph.D. and Dow R. Wilson continued in office following the Annual Meeting.

Proposal No. 2 The non-binding advisory vote to approve the compensation of the


               Company's named executive officers was approved as set forth
               below.



    For      Against   Abstain Broker Non-Vote
216,898,569 28,651,613 517,124   20,770,508

Proposal No. 3 The proposal to ratify the Audit and Finance Committee's


               appointment of PricewaterhouseCoopers LLP as the Company's
               independent registered public accounting firm for the 2022 fiscal
               year was approved as set forth below.



    For      Against   Abstain Broker Non-Vote(1)
248,388,336 17,949,546 500,033        -0-

Proposal No. 4 The stockholder proposal regarding the right to call a special


               meeting was approved as set forth below.



    For      Against   Abstain Broker Non-Vote(1)
200,652,664 44,840,290 574,270     20,770,508

(1) Pursuant to the rules of the New York Stock Exchange, this proposal


    constituted a routine matter. Therefore, brokers were permitted to vote
    without receipt of instructions from beneficial owners.

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