Presentation slides 29 September 2022: Interim Results for the Six Months Ended 30 June 2022

Transforming cancer care

Interim Results for the

six months ended 30 June 2022

Andrew Newland and Ian Griffiths

29 September 2022

LSE AIM:AGL OTCQX: ANPCY

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© ANGLE plc 2022

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ANGLE - Transforming cancer care

National Cancer Institute United States:

An estimated 40% of men and women will be diagnosed with cancer during their lifetime

Our Mission:

Enable personalized cancer care with a simple blood test to guide treatment, improving patient outcomes and reducing healthcare expenditure

Our Solution:

The Parsortix system

• first and only FDA cleared product for harvesting CTCs for subsequent analysis
• ANGLE believes it provides the best sample of a patient's cancer from a liquid biopsy
• enables effective, affordable, repeat testing of intact cells

© ANGLE plc 2022

Parsortix® instrument

Parsortix® cassette

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First Half Highlights

Breakthrough FDA clearance sets platform for growth

Half year

• FDA De Novo Class II medical device clearance in metastatic breast cancer achieved
• Global pharma services business momentum encouraging
• Prostate cancer partnership established with Solaris Health, a major United States urology group

Post period end

• Positive headline results from ovarian cancer verification study
• Presentation of Pap stain assay, offering low cost CTC analysis solution
• Capital raise of £20.1 million

© ANGLE plc 2022

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Financial Results for six months ended 30 June 2022

	Six months ended	Six months ended
	30 June 2022	30 June 2021
Statement of Comprehensive Income	£'000	£'000
Revenue	419	296
Cost of sales	(160)	(77)
Gross profit	259	219
Operating costs (net of grant income)	(10,625)	(8,881)
Tax credit and net finance costs	1,145	979
Loss for the period	(9,221)	(7,683)
	30 June 2022	31 December 2021
Statement of Financial Position	£'000	£'000
Trade and other receivables and R&D tax credit	7,715	5,779
Inventories	1,734	1,748
Cash	20,497	31,839
Property, plant and equipment and right-of-use assets	8,266	4,376
Intangible assets	3,590	3,573
Total assets	41,802	47,315

Comments

• Revenue increased by 42%
• Gross margin at 62%
• Planned expenditure of £10.6 million
• Cash position of £20.5 million
• R&D tax credit due of £4.5 million
• Fundraise of £18.9 million (net) July 2022

© ANGLE plc 2022

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