Item 1.01 Entry into a Material Definitive Agreement.

On May 24, 2022, in connection with the closing of the transactions contemplated by the Merger Agreement, Halozyme entered into that certain Credit Agreement (the "Credit Agreement") with Bank of America, N.A., as Administrative Agent, Swing Line Lender and an L/C Issuer, and the other lenders and L/C Issuers party thereto, evidencing a credit facility (the "Facility") that provides for (x) a $350 million revolving credit facility (the "Revolving Credit Facility") and (y) a $250 million term loan facility (the "Term Facility"). The proceeds of the Term Facility and the initial borrowings under the Revolving Credit Facility, in addition to a portion of Halozyme's existing cash on hand, were used to pay the Merger Consideration, refinance the Company's existing indebtedness and pay fees and expenses in connection with the foregoing.

Halozyme, Inc., a wholly-owned subsidiary of Halozyme, and the Company guarantee Halozyme's obligations under the Credit Agreement. The Facility will mature on November 30, 2026, unless either the Revolving Credit Facility or the Term Facility is extended prior to such date in accordance with the Credit Agreement.

The Credit Agreement contains an expansion feature, which allows Halozyme, subject to certain conditions, to increase the aggregate principal amount of the Facility, provided Halozyme remains in compliance with underlying financial covenants on a pro forma basis including the consolidated interest coverage ratio and the consolidated net leverage ratio covenants set forth in the Credit Agreement, and the consolidated net leverage ratio shall be not greater than 0.25:1.00 less than the consolidated net leverage ratio then permitted under the Credit Agreement.

In addition to paying interest on the outstanding principal under the Facility, Halozyme will pay (i) a commitment fee in respect of the unutilized commitments thereunder and (ii) customary letter of credit fees and agency fees. The commitment fees range from 0.15% to 0.35% per annum based on Halozyme's consolidated net leverage ratio.

Substantially all of the assets of Halozyme and the Guarantors (including the Company) are pledged as collateral under the Facility (subject to customary exceptions and excluding real property and intellectual property) pursuant to the terms set forth in the Security Agreement (as defined in the Credit Agreement) and Pledge Agreement, each dated as of May 24, 2022, and each executed in favor of the administrative agent by Halozyme and the Guarantors. Following the Closing, borrowings under the Revolving Credit Facility are to be used by Halozyme to provide financing for working capital and other general corporate purposes, including potential acquisitions.

Borrowings under the Facility bear interest, at Halozyme's option, at a rate equal to an applicable margin plus: (a) the applicable Term SOFR (as defined in . . .

Item 1.02 Termination of Material Definitive Agreement.

In connection with the consummation of the Merger, on May 24, 2022, the Company repaid in full all amounts outstanding and terminated its Credit Agreement, dated as of November 1, 2021, by and among the Company, the Lenders referred to therein and Wells Fargo Bank, National Association, as administrative agent.

Item 2.01 Completion of Acquisition or Disposition of Assets.

The disclosures under the Introductory Note and Item 3.01 are incorporated herein by reference.

Item 2.04 Triggering Events That Accelerate or Increase a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement.

The disclosures under the Introductory Note and Item 1.02 are incorporated herein by reference.

Item 3.01 Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing.

The disclosures under the Introductory Note are incorporated herein by reference.

On May 24, 2022, the Company (i) notified the Nasdaq Stock Market LLC ("Nasdaq") of the consummation of the Merger and (ii) requested that Nasdaq (A) suspend trading of the Shares effective before the opening of trading on May 24, 2022 and (B) file with the SEC a Form 25 Notification of Removal from Listing and/or Registration to delist and deregister the Shares under Section 12(b) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). As a result, the Shares will no longer be listed on Nasdaq. The Company intends to file with the SEC a certification on Form 15 under the Exchange Act, requesting the suspension of the Company's reporting obligations under Sections 13 and 15(d) of the Exchange Act.

Item 3.03 Material Modification to Rights of Security Holders.

The disclosures under the Introductory Note, Item 3.01, Item 5.01 and Item 5.03 are incorporated herein by reference.

Item 5.01 Changes in Control of Registrant.

The disclosures under the Introductory Note, Item 3.01, Item 5.02 and Item 5.03 are incorporated herein by reference.

As a result of the consummation of the Offer and the Merger pursuant to Section 251(h) of the DGCL, on May 24, 2022, there was a change in control of the Company. At the Effective Time, the Company became a wholly-owned subsidiary of Halozyme.

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Pursuant to the Merger Agreement, effective as of the Effective Time, Leonard S. Jacob, M.D., Ph.D., Thomas J. Garrity, Peter S. Greenleaf, Anton Gueth, Robert P. Roche Jr., Karen Smith, M.D., Ph.D., Carmen B. Volkart, and Robert F. Apple each ceased to be directors of the Company and members of any committee of the Company's board of directors. These departures were not a result of any disagreement between the Company and the directors on any matter relating to the Company's operations, policies or practices.

Pursuant to the Merger Agreement, effective as of the Effective Time, Robert F. Apple, Fred M. Powell, Peter J. Graham, Esq. and Peter C. Richardson, M.D. each ceased to be officers of the Company.

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Further, pursuant to the Merger Agreement and effective immediately after the Effective Time, each of Helen Torley, M.B. Ch.B., M.R.C.P., and Nicole LaBrosse became the officers and directors of the Surviving Corporation. Information regarding the new directors and officers of the Surviving Corporation has been previously disclosed in the Tender Offer Statement on Schedule TO filed by Halozyme and Purchaser with the SEC on April 26, 2022 (together with the exhibits and annexes thereto and as amended or supplemented from time to time), which is incorporated herein by reference.

Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.

Pursuant to the terms of the Merger Agreement, effective as of the Effective Time, the Company's certificate of incorporation, as in effect immediately prior to the Effective Time, was amended and restated in its entirety (the "Amended and Restated Certificate of Incorporation"). In addition, pursuant to the terms of the Merger Agreement, effective as of the Effective Time, the Company's amended and restated by-laws, as in effect immediately prior to the Effective Time, were amended and restated in their entirety (the "Second Amended and Restated By-Laws").

Copies of the Amended and Restated Certificate of Incorporation and the Second Amended and Restated By-Laws are filed as Exhibits 3.1 and 3.2, respectively, to this Current Report on Form 8-K, and are incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.



(d) Exhibits

Exhibit
Number       Description

2.1            Agreement and Plan of Merger, dated April 12, 2022, by and among
             Halozyme, Purchaser and the Company (incorporated by reference to
             Exhibit 2.1 to the Company's Current Report on Form 8-K filed with the
             SEC on April 13, 2022).*

3.1            Amended and Restated Certificate of Incorporation of the Surviving
             Corporation, dated May 24, 2022.

3.2            Second Amended and Restated By-Laws of the Surviving Corporation,
             dated May 24, 2022.

10.1         Credit Agreement, dated as of May 24, 2022, by and among Halozyme
             Therapeutics, Inc., the Guarantors, Bank of America N.A. and each of
             those additional Lenders that are a party to such agreement
             (incorporated by reference to Exhibit 10.1 to Halozyme's Current
             Report on Form 8-K (File No. 001-32335) filed with the SEC on May 24,
             2022).

10.2         Security Agreement, dated as of May 24, 2022, by and among Halozyme
             Therapeutics, Inc., the Guarantors and Bank of America N.A
             (incorporated by reference to Exhibit 10.2 to Halozyme's Current
             Report on Form 8-K (File No. 001-32335) filed with the SEC on May 24,
             2022).

104          Cover Page Interactive Date File (embedded within the Inline XBRL
             document)


* Schedules to the Agreement and Plan of Merger have been omitted pursuant to

Item 601(b)(2) of Regulation S-K. The registrant will furnish copies of any

such schedules to the U.S. Securities and Exchange Commission upon request.

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