Avenue Therapeutics, Inc. announced that on December 1, 2020, Thomas G. Moore informed the Company of his decision to resign from the Board of Directors of the Company, effective December 31, 2020. His resignation was not the result from any disagreement with the Company, or any matter related to the Company’s operations, policies or practices, the Company’s management or the Board. Dr. Moore was an independent director nominated by InvaGen Pharmaceuticals Inc.