HERCULES, Calif. (AP) _ Bio-Rad Laboratories Inc. (BIO.B) on Thursday reported a third-quarter loss of $164.2 million, after reporting a profit in the same period a year earlier.

On a per-share basis, the Hercules, California-based company said it had a loss of $5.52. Earnings, adjusted for non-recurring costs, came to $2.60 per share.

The maker of instruments used in biomedical research posted revenue of $680.8 million in the period.

Bio-Rad shares have fallen 46% since the beginning of the year. In the final minutes of trading on Thursday, shares hit $390.84, a decrease of 50% in the last 12 months.

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