Biocytogen Pharmaceuticals (Beijing) Co., Ltd. announced that it has entered into an Exclusive Option and License Agreement with Radiance Biopharma Inc. The agreement grants Radiance an option to license from Biocytogen a first-in-class fully human anti-HER2/TROP2 bispecific antibody-drug conjugate (BsADC) for therapeutic product development, manufacturing and commercialization for all human indications worldwide. HER2 and TROP2 are two tumor-associated antigens (TAAs) that have been found to be commonly expressed and co-expressed by multiple tumor types, including breast, gastric, colorectal, bladder, pancreatic, and non-small-cell lung cancer. Under the terms of the agreement, upon the option exercised, Biocytogen will be entitled to receive an option fee, licensing fee, development and commercialization milestone payments, as well as single-digit royalties on net sales.

In addition, Biocytogen has the right to collect the sharing of sublicensing fee, if any, between Radiance and third party.