Endo International plc announced the launch of their first-ever XIAFLEX? (collagenase clostridium histolyticum) television commercial, Bent Carrot. The spot introduces men to XIAFLEX as the first and only nonsurgical FDA-approved treatment for Peyronie's disease (PD) and encourages them to seek treatment if they believe they may have the condition, in which a buildup of fibrous scar tissue (plaque) causes a curvature of the penis. XIAFLEX is the first and only FDA-approved treatment for Peyronie's disease (PD), a men's health condition that may affect 1 in 10 men and can lead to a curvature with a plaque that can be felt in the penis. Bent Carrot" encourages and empowers men to recognize if they have an erectile curvature caused by a buildup of scar tissue, to seek diagnosis and to ask for XIAFLEX to help start their treatment journey. Over the last two years, Endo has gathered insights via market research from men living with PD. For these men, the journey from diagnosis to treatment can take upward of seven years. Often, men are misdiagnosed and/or are frustrated by their journey to address their erectile curvature. Integrated Campaign Details: The 60-second TV commercial features the image of a bent carrot to symbolize PD. It will run on prime-time TV (including networks like USA and news programs such as "CBS Evening News with Norah O'Donnell"), streaming services (including Hulu, Paramount+ and Discovery+) and online beginning in October. The commercial is part of a larger, surround-sound campaign that includes radio and streaming music service ads, social media ads on platforms where patients are active, digital ads and partnerships on health-focused websites, signage and educational materials in doctors' offices and partnerships with industry organizations. Why the carrot? It's a friendly, visual approach to a condition that often causes embarrassment and may feel too intimate to discuss. The single, simple metaphor is memorable and easy to recall. The campaign uses positive and lively?but not funny?creative to visualize PD in a way that's factual, understandable and solution-oriented. XIAFLEX is a prescription medicine used to treat adult men with Peyronie's disease who have a "plaque" that can be felt and a curve in their penis greater than 30 degrees when treatment is started. It is not known if XIAFLEX is safe and effective in children under the age of 18.