G1 Therapeutics, Inc. announced that COSELA(R) (trilaciclib) has been recommended as a myeloid supportive agent in the updated American Society of Clinical Oncology (ASCO) small cell lung cancer (SCLC) guidelines for patients with untreated or previously treated extensive-stage small cell lung cancer (ES-SCLC) who are undergoing treatment with chemotherapy or chemoimmunotherapy. COSELA is indicated to decrease the incidence of chemotherapy-induced myelosuppression in adult patients when administered prior to a platinum/etoposide-containing regimen or topotecan-containing regimen for ES-SCLC. Published on October 11, 2023, the SCLC guidelines, entitled "Systemic Therapy for SCLC: ASCO-Ontario Health (Cancer Care Ontario) Guideline" (Khurshid et al.) provide evidence-based recommendations to practicing clinicians on the management of patients with SCLC.

ASCO's clinical practice guidelines outline appropriate methods of treatment and care for clinicians and address specific clinical situations (disease-oriented) or the use of approved medical products, procedures, or tests (modality-oriented). Multidisciplinary panels of experts, including patient advocates, develop ASCO's clinical practice guidelines. For more information on ASCO's guidelines in thoracic cancer, including the SCLC guidelines.