Immix Biopharma, Inc. announced that it will host a virtual KOL event to discuss its BCMA-Targeted CAR-T cell therapy candidate NXC-201, in development for relapsed/refractory AL amyloidosis (R/R ALA) and relapsed/refractory multiple myeloma (R/R MM) with planned expansion into autoimmune indications, on November 29, 2023 at 4:15 pm ET. The event will feature Heather Landau, MD (Director of Amyloidosis Program, Memorial Sloan-Kettering Cancer Center), Vaishali Sanchorawala, MD (Professor, Boston University School of Medicine), and Susan Bal, MD (Assistant Professor, University of Alabama at Birmingham) who will discuss the current treatment paradigm for patients with relapsed/refractory AL Amyloidosis and the NEXICART-1 study of NXC-201 as a potential chimeric antigen receptor T (CAR-T) treatment option. NXC-201 is a BCMA-targeted investigational CAR-T cell therapy.

NXC-201 has been dosed in more than 70 patients to date and has demonstrated promising Phase 1/2a data in ALA, with a 100% overall response rate (9/9) in heavily pre-treated relapsed/refractory AL amyloidosis patients, as well as a 95% overall response rate, with a median of 11.9 months of follow-up, in patients with R/R MM (36/38 heavily pre-treated patients). On November 21, 2023, IMMX announced receipt of IND clearance to expand NXC-201 dosing into the U.S. NXC-201 has been selected for an oral presentation and a poster presentation at the American Society for Hematology 65th Annual Meeting on December 10, and December 11, 2023. NXC-201 has been awarded Orphan Drug Designation (ODD) by the FDA in both AL Amyloidosis and multiple myeloma.