Integrum (publ) announced that the company has established a Center of Excellence at the Center for Complex Endoprosthetics, Osseointegration and Bionics in Kyiv, with the intention to spearhead orthopedic treatment using OPRA? Implant System in individuals who have suffered limb loss. The need for amputee care in Ukraine has increased rapidly since the Russian invasion.

More than 20,000 individuals have lost extremities, which has put a high strain on the healthcare system and created a significant need for swift actions on an infrastructure level. The new Center of Excellence is operational following recent visits to Ukraine by Dr. Brånemark. Two senior surgeons have already been trained and certified to perform both transfemoral and transhumeral surgeries using Integrum's innovative OPRA?

Implant System. More than 10 patients have already been treated using Integrum's implant system. This was initially done as a pro bono initiative by Dr. Brånemark and Integrum but is now also part of Integrum's commercial operations.