Jaguar Health, Inc. reported consolidated operating results for the third quarter ended September 30, 2021. Mytesi (crofelemer) prescription volume, the metric the Company believes to be the best indicator of patient demand, increased 7.6% in the third quarter of 2021 over the second quarter of 2021, and new Mytesi prescriptions increased 9.0% during the same period. Mytesi total prescription volume remained the same in the third quarter of 2021 over the third quarter of 2020 and new Mytesi prescriptions increased by 10.5% during the same period.