Upon the Effective Time, in accordance with the terms of the Merger Agreement, all of the directors of Karuna Therapeutics, Inc. ceased to be directors. No director was terminated or resigned because of any disagreement with Karuna, its management or its board of directors on any matter relating to its operations, policies or practices. Immediately following the Effective Time, the directors of Miramar Merger Sub Inc. at the Effective Time became the directors of the Karuna Therapeutics, Inc. The directors of Miramar Merger Sub Inc. at the Effective Time were Konstantina Katcheves, Sandra Ramos-Alves and Kimberly M. Jablonski.

Immediately following the Effective Time, all executive officers of Karuna immediately prior to the Effective Time were removed from their respective positions as the executive officers of the Karuna. Concurrently with such officers? removal, Sandra Ramos-Alves was appointed to serve as President and Treasurer of the Karuna, Sophia Park was appointed to serve as Vice President of the Surviving Corporation, Scott Matarese was appointed to serve as Vice President of the Surviving Corporation, Kimberly M. Jablonski was appointed to serve as Vice President and Secretary of the Surviving Corporation, Lisa A. Atkins was appointed to serve as Assistant Secretary of the Surviving Corporation and Elisabeth Bradley was appointed to serve as Assistant Secretary of the Surviving Corporation.