Cellares and Lyell Immunopharma announced Lyell will evaluate Cellares' automated manufacturing platform, the Cell Shuttle, through Cellares' Technology Adoption Partnership (TAP) program. LYL797 is enhanced with Lyell's novel genetic and epigenetic reprogramming technologies designed to generate highly tumor-reactive, longer-lasting functional T cells. Lyell is enrolling patients with triple-negative breast cancer and non-small cell lung cancer in a Phase 1 clinical trial evaluating LYL797.

Cellares' TAP program offers cell therapy developers a swift and low-risk pathway to embrace the company's automated manufacturing technology for their pipeline products. Lyell is utilizing this program to assess the automated manufacturing process and generate data that validates the Cell Shuttle's viability as a manufacturing option for CAR T-cell therapies. Cellares partners with prominent cell therapy developers through its TAP program to integrate the Cell Shuttle as a GMP manufacturing solution in both clinical and commercial stages at their IDMO Smart Factories.